{
  "resourceType" : "StructureDefinition",
  "id" : "da1af6de-fd9a-4352-a743-fbf40f1d85a8-65",
  "url" : "http://hl7.org/fhir/comparison/StructureDefinition/da1af6de-fd9a-4352-a743-fbf40f1d85a8-65",
  "name" : "UnionMedicationStatementIPSAndMedicationStatementEuCore",
  "title" : "Union of MedicationStatement (IPS) And MedicationStatement (EU core)",
  "status" : "active",
  "date" : "2026-02-25T10:02:29+01:00",
  "jurisdiction" : [{
    "coding" : [{
      "system" : "http://unstats.un.org/unsd/methods/m49/m49.htm",
      "code" : "001",
      "display" : "World"
    }]
  },
  {
    "coding" : [{
      "system" : "http://unstats.un.org/unsd/methods/m49/m49.htm",
      "code" : "150",
      "display" : "Europe"
    }]
  }],
  "snapshot" : {
    "element" : [{
      "path" : "MedicationStatement",
      "short" : "Record of medication being taken by a patient",
      "definition" : "A record of a medication that is being consumed by a patient.   A MedicationStatement may indicate that the patient may be taking the medication now or has taken the medication in the past or will be taking the medication in the future.  The source of this information can be the patient, significant other (such as a family member or spouse), or a clinician.  A common scenario where this information is captured is during the history taking process during a patient visit or stay.   The medication information may come from sources such as the patient's memory, from a prescription bottle,  or from a list of medications the patient, clinician or other party maintains. \n\nThe primary difference between a medication statement and a medication administration is that the medication administration has complete administration information and is based on actual administration information from the person who administered the medication.  A medication statement is often, if not always, less specific.  There is no required date/time when the medication was administered, in fact we only know that a source has reported the patient is taking this medication, where details such as time, quantity, or rate or even medication product may be incomplete or missing or less precise.  As stated earlier, the medication statement information may come from the patient's memory, from a prescription bottle or from a list of medications the patient, clinician or other party maintains.  Medication administration is more formal and is not missing detailed information.",
      "comment" : "When interpreting a medicationStatement, the value of the status and NotTaken needed to be considered:\rMedicationStatement.status + MedicationStatement.wasNotTaken\rStatus=Active + NotTaken=T = Not currently taking\rStatus=Completed + NotTaken=T = Not taken in the past\rStatus=Intended + NotTaken=T = No intention of taking\rStatus=Active + NotTaken=F = Taking, but not as prescribed\rStatus=Active + NotTaken=F = Taking\rStatus=Intended +NotTaken= F = Will be taking (not started)\rStatus=Completed + NotTaken=F = Taken in past\rStatus=In Error + NotTaken=N/A = In Error.",
      "min" : 0,
      "max" : "*",
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "not(parent::f:contained and f:contained)"
        }],
        "key" : "dom-2",
        "severity" : "error",
        "human" : "If the resource is contained in another resource, it SHALL NOT contain nested Resources",
        "expression" : "contained.contained.empty()",
        "source" : "http://hl7.org/fhir/StructureDefinition/DomainResource"
      },
      {
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "not(exists(for $id in f:contained/*/f:id/@value return $contained[not(parent::*/descendant::f:reference/@value=concat('#', $contained/*/id/@value) or descendant::f:reference[@value='#'])]))"
        }],
        "key" : "dom-3",
        "severity" : "error",
        "human" : "If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource",
        "expression" : "contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()",
        "source" : "http://hl7.org/fhir/StructureDefinition/DomainResource"
      },
      {
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "not(exists(f:contained/*/f:meta/f:versionId)) and not(exists(f:contained/*/f:meta/f:lastUpdated))"
        }],
        "key" : "dom-4",
        "severity" : "error",
        "human" : "If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated",
        "expression" : "contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()",
        "source" : "http://hl7.org/fhir/StructureDefinition/DomainResource"
      },
      {
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "not(exists(f:contained/*/f:meta/f:security))"
        }],
        "key" : "dom-5",
        "severity" : "error",
        "human" : "If a resource is contained in another resource, it SHALL NOT have a security label",
        "expression" : "contained.meta.security.empty()",
        "source" : "http://hl7.org/fhir/StructureDefinition/DomainResource"
      },
      {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice",
          "valueBoolean" : true
        },
        {
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice-explanation",
          "valueMarkdown" : "When a resource has no narrative, only systems that fully understand the data can display the resource to a human safely. Including a human readable representation in the resource makes for a much more robust eco-system and cheaper handling of resources by intermediary systems. Some ecosystems restrict distribution of resources to only those systems that do fully understand the resources, and as a consequence implementers may believe that the narrative is superfluous. However experience shows that such eco-systems often open up to new participants over time."
        },
        {
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "exists(f:text/h:div)"
        }],
        "key" : "dom-6",
        "severity" : "warning",
        "human" : "A resource should have narrative for robust management",
        "expression" : "text.`div`.exists()",
        "source" : "http://hl7.org/fhir/StructureDefinition/DomainResource"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "Entity. Role, or Act"
      },
      {
        "identity" : "workflow",
        "map" : "Event"
      },
      {
        "identity" : "rim",
        "map" : "SubstanceAdministration"
      }]
    },
    {
      "path" : "MedicationStatement.id",
      "short" : "Logical id of this artifact",
      "definition" : "The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.",
      "comment" : "The only time that a resource does not have an id is when it is being submitted to the server using a create operation.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl" : "id"
        }],
        "code" : "http://hl7.org/fhirpath/System.String"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true
    },
    {
      "path" : "MedicationStatement.meta",
      "short" : "Metadata about the resource",
      "definition" : "The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "Meta"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true
    },
    {
      "path" : "MedicationStatement.implicitRules",
      "short" : "A set of rules under which this content was created",
      "definition" : "A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.",
      "comment" : "Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "uri"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : true,
      "isSummary" : true
    },
    {
      "path" : "MedicationStatement.language",
      "short" : "left: Language of the resource content; right: Language of the statement",
      "definition" : "The base language in which the resource is written.",
      "comment" : "Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies  to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute).",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "code"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "strength" : "preferred",
        "description" : "A human language.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/languages|4.0.1"
      }
    },
    {
      "path" : "MedicationStatement.text",
      "short" : "Text summary of the resource, for human interpretation",
      "definition" : "A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it \"clinically safe\" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.",
      "comment" : "Contained resources do not have narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied).  This may be necessary for data from legacy systems where information is captured as a \"text blob\" or where text is additionally entered raw or narrated and encoded information is added later.",
      "alias" : ["narrative",
      "html",
      "xhtml",
      "display"],
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "Narrative"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "Act.text?"
      }]
    },
    {
      "path" : "MedicationStatement.contained",
      "short" : "Contained, inline Resources",
      "definition" : "These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope.",
      "comment" : "This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags In their meta elements, but SHALL NOT have security labels.",
      "alias" : ["inline resources",
      "anonymous resources",
      "contained resources"],
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "Resource"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "path" : "MedicationStatement.extension",
      "short" : "left: Additional content defined by implementations; right: Extension",
      "definition" : "left: May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.; right: An Extension",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])"
        }],
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "path" : "MedicationStatement.modifierExtension",
      "short" : "Extensions that cannot be ignored",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions].",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])"
        }],
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "mustSupport" : false,
      "isModifier" : true,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "path" : "MedicationStatement.identifier",
      "short" : "left: External identifier; right: Medication Statement Identifier",
      "definition" : "Identifiers associated with this Medication Statement that are defined by business processes and/or used to refer to it when a direct URL reference to the resource itself is not appropriate. They are business identifiers assigned to this resource by the performer or other systems and remain constant as the resource is updated and propagates from server to server.",
      "comment" : "This is a business identifier, not a resource identifier.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "Identifier"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "workflow",
        "map" : "Event.identifier"
      },
      {
        "identity" : "w5",
        "map" : "FiveWs.identifier"
      },
      {
        "identity" : "rim",
        "map" : ".id"
      }]
    },
    {
      "path" : "MedicationStatement.basedOn",
      "short" : "Fulfils plan, proposal or order",
      "definition" : "A plan, proposal or order that is fulfilled in whole or in part by this event.",
      "requirements" : "Allows tracing of authorization for the event and tracking whether proposals/recommendations were acted upon.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/MedicationRequest|4.0.1",
        "http://hl7.org/fhir/StructureDefinition/CarePlan|4.0.1",
        "http://hl7.org/fhir/StructureDefinition/ServiceRequest|4.0.1"]
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "workflow",
        "map" : "Event.basedOn"
      },
      {
        "identity" : "rim",
        "map" : ".outboundRelationship[typeCode=FLFS].target[classCode=SBADM or PROC or PCPR or OBS, moodCode=RQO orPLAN or PRP]"
      }]
    },
    {
      "path" : "MedicationStatement.partOf",
      "short" : "Part of referenced event",
      "definition" : "A larger event of which this particular event is a component or step.",
      "requirements" : "This should not be used when indicating which resource a MedicationStatement has been derived from.  If that is the use case, then MedicationStatement.derivedFrom should be used.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/MedicationAdministration|4.0.1",
        "http://hl7.org/fhir/StructureDefinition/MedicationDispense|4.0.1",
        "http://hl7.org/fhir/StructureDefinition/MedicationStatement|4.0.1",
        "http://hl7.org/fhir/StructureDefinition/Procedure|4.0.1",
        "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1"]
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "workflow",
        "map" : "Event.partOf"
      },
      {
        "identity" : "rim",
        "map" : ".outboundRelationship[typeCode=COMP]/target[classCode=SPLY or SBADM or PROC or OBS,moodCode=EVN]"
      }]
    },
    {
      "path" : "MedicationStatement.status",
      "short" : "left: active | completed | entered-in-error | intended | stopped | on-hold | unknown | not-taken; right: State of the medication",
      "definition" : "A code representing the patient or other source's judgment about the state of the medication used that this statement is about.  Generally, this will be active or completed.",
      "comment" : "left: In the scope of the IPS the entered-in-error concept is not allowed.; right: MedicationStatement is a statement at a point in time.  The status is only representative at the point when it was asserted.  The value set for MedicationStatement.status contains codes that assert the status of the use of the medication by the patient (for example, stopped or on hold) as well as codes that assert the status of the medication statement itself (for example, entered in error).\r\rThis element is labeled as a modifier because the status contains codes that mark the resource as not currently valid.",
      "min" : 1,
      "max" : "1",
      "type" : [{
        "code" : "code"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : true,
      "isSummary" : true,
      "binding" : {
        "strength" : "required",
        "description" : "A coded concept indicating the current status of a MedicationStatement.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/medication-statement-status|4.0.1"
      },
      "mapping" : [{
        "identity" : "workflow",
        "map" : "Event.status"
      },
      {
        "identity" : "w5",
        "map" : "FiveWs.status"
      },
      {
        "identity" : "rim",
        "map" : ".statusCode"
      }]
    },
    {
      "path" : "MedicationStatement.statusReason",
      "short" : "left: Reason for current status; right: Reason for the 'exception' statuses of the medication",
      "definition" : "Captures the reason for the current state of the MedicationStatement.",
      "comment" : "This is generally only used for \"exception\" statuses such as \"not-taken\", \"on-hold\", \"cancelled\" or \"entered-in-error\". The reason for performing the event at all is captured in reasonCode, not here.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "strength" : "example",
        "description" : "A coded concept indicating the reason for the status of the statement.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/reason-medication-status-codes|4.0.1"
      },
      "mapping" : [{
        "identity" : "workflow",
        "map" : "Event.statusReason"
      },
      {
        "identity" : "rim",
        "map" : ".inboundRelationship[typeCode=SUBJ].source[classCode=CACT, moodCode=EVN].reasonCOde"
      }]
    },
    {
      "path" : "MedicationStatement.category",
      "short" : "left: Type of medication usage; right: Type of intended use",
      "definition" : "Indicates where the medication is expected to be consumed or administered.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true,
      "binding" : {
        "strength" : "preferred",
        "description" : "A coded concept identifying where the medication included in the MedicationStatement is expected to be consumed or administered.",
        "valueSet" : "http://hl7.org/fhir/comparison/ValueSet/da1af6de-fd9a-4352-a743-fbf40f1d85a8-68"
      },
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.class"
      },
      {
        "identity" : "rim",
        "map" : ".inboundRelationship[typeCode=COMP].source[classCode=OBS, moodCode=EVN, code=\"type of medication usage\"].value"
      }]
    },
    {
      "path" : "MedicationStatement.medication[x]",
      "short" : "What medication was taken",
      "definition" : "left: Identifies the medication being administered or the reason for absent or unknown Medication. This is either a link to a resource representing the details of the medication or a simple attribute carrying a code. To improve global interoperability, it is strongly encouraged that the reference to a medication resource is used, limiting the usage of the medicationCodeableConcept only to the cases in which no other information than a simple code is available.; right: Identifies the medication being administered. This is either a link to a resource representing the details of the medication or a simple attribute carrying a code that identifies the medication from a known list of medications.",
      "comment" : "If only a code is specified, then it needs to be a code for a specific product. If more information is required, then the use of the medication resource is recommended.  For example, if you require form or lot number, then you must reference the Medication resource.",
      "min" : 1,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      },
      {
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/uv/ips/StructureDefinition/Medication-uv-ips",
        "#sd-Medication-uv-ips-medication-eu-core"]
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : true,
      "isModifier" : false,
      "isSummary" : true,
      "binding" : {
        "strength" : "preferred",
        "description" : "SNOMED CT medications (Medicinal product) or a code for absent/unknown medication",
        "valueSet" : "http://hl7.org/fhir/uv/ips/ValueSet/medication-uv-ips"
      },
      "mapping" : [{
        "identity" : "workflow",
        "map" : "Event.code"
      },
      {
        "identity" : "w5",
        "map" : "FiveWs.what[x]"
      },
      {
        "identity" : "rim",
        "map" : ".participation[typeCode=CSM].role[classCode=ADMM or MANU]"
      }]
    },
    {
      "path" : "MedicationStatement.subject",
      "short" : "Who is/was taking  the medication",
      "definition" : "The person, animal or group who is/was taking the medication.",
      "min" : 1,
      "max" : "1",
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/uv/ips/StructureDefinition/Patient-uv-ips",
        "#sd-Patient-uv-ips-patient-eu-core"]
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : true,
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "workflow",
        "map" : "Event.subject"
      },
      {
        "identity" : "w5",
        "map" : "FiveWs.subject[x]"
      },
      {
        "identity" : "v2",
        "map" : "PID-3-Patient ID List"
      },
      {
        "identity" : "rim",
        "map" : ".participation[typeCode=SBJ].role[classCode=PAT]"
      },
      {
        "identity" : "w5",
        "map" : "FiveWs.subject"
      }]
    },
    {
      "id" : "MedicationStatement.subject.id",
      "path" : "MedicationStatement.subject.id",
      "representation" : ["xmlAttr"],
      "short" : "Unique id for inter-element referencing",
      "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Element.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl" : "string"
        }],
        "code" : "http://hl7.org/fhirpath/System.String"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationStatement.subject.extension",
      "path" : "MedicationStatement.subject.extension",
      "slicing" : {
        "discriminator" : [{
          "type" : "value",
          "path" : "url"
        }],
        "description" : "Extensions are always sliced by (at least) url",
        "rules" : "open"
      },
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Element.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])"
        }],
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationStatement.subject.reference",
      "extension" : [{
        "extension" : [{
          "url" : "code",
          "valueCode" : "SHALL:populate-if-known"
        },
        {
          "url" : "actor",
          "valueCanonical" : "http://hl7.org/fhir/uv/ips/ActorDefinition/Creator"
        },
        {
          "url" : "http://hl7.org/fhir/tools/StructureDefinition/snapshot-source",
          "valueCanonical" : "http://hl7.org/fhir/uv/ips/StructureDefinition/MedicationStatement-uv-ips|2.0.0"
        }],
        "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
      },
      {
        "extension" : [{
          "url" : "code",
          "valueCode" : "SHALL:handle"
        },
        {
          "url" : "actor",
          "valueCanonical" : "http://hl7.org/fhir/uv/ips/ActorDefinition/Consumer"
        },
        {
          "url" : "http://hl7.org/fhir/tools/StructureDefinition/snapshot-source",
          "valueCanonical" : "http://hl7.org/fhir/uv/ips/StructureDefinition/MedicationStatement-uv-ips|2.0.0"
        }],
        "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
      }],
      "path" : "MedicationStatement.subject.reference",
      "short" : "Literal reference, Relative, internal or absolute URL",
      "definition" : "A reference to a location at which the other resource is found. The reference may be a relative reference, in which case it is relative to the service base URL, or an absolute URL that resolves to the location where the resource is found. The reference may be version specific or not. If the reference is not to a FHIR RESTful server, then it should be assumed to be version specific. Internal fragment references (start with '#') refer to contained resources.",
      "comment" : "Using absolute URLs provides a stable scalable approach suitable for a cloud/web context, while using relative/logical references provides a flexible approach suitable for use when trading across closed eco-system boundaries.   Absolute URLs do not need to point to a FHIR RESTful server, though this is the preferred approach. If the URL conforms to the structure \"/[type]/[id]\" then it should be assumed that the reference is to a FHIR RESTful server.",
      "min" : 1,
      "max" : "1",
      "base" : {
        "path" : "Reference.reference",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "string"
      }],
      "condition" : ["ref-1"],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : true,
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "MedicationStatement.subject.type",
      "path" : "MedicationStatement.subject.type",
      "short" : "Type the reference refers to (e.g. \"Patient\")",
      "definition" : "The expected type of the target of the reference. If both Reference.type and Reference.reference are populated and Reference.reference is a FHIR URL, both SHALL be consistent.\n\nThe type is the Canonical URL of Resource Definition that is the type this reference refers to. References are URLs that are relative to http://hl7.org/fhir/StructureDefinition/ e.g. \"Patient\" is a reference to http://hl7.org/fhir/StructureDefinition/Patient. Absolute URLs are only allowed for logical models (and can only be used in references in logical models, not resources).",
      "comment" : "This element is used to indicate the type of  the target of the reference. This may be used which ever of the other elements are populated (or not). In some cases, the type of the target may be determined by inspection of the reference (e.g. a RESTful URL) or by resolving the target of the reference; if both the type and a reference is provided, the reference SHALL resolve to a resource of the same type as that specified.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Reference.type",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "uri"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "FHIRResourceTypeExt"
        }],
        "strength" : "extensible",
        "description" : "Aa resource (or, for logical models, the URI of the logical model).",
        "valueSet" : "http://hl7.org/fhir/ValueSet/resource-types|4.0.1"
      },
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "MedicationStatement.subject.identifier",
      "path" : "MedicationStatement.subject.identifier",
      "short" : "Logical reference, when literal reference is not known",
      "definition" : "An identifier for the target resource. This is used when there is no way to reference the other resource directly, either because the entity it represents is not available through a FHIR server, or because there is no way for the author of the resource to convert a known identifier to an actual location. There is no requirement that a Reference.identifier point to something that is actually exposed as a FHIR instance, but it SHALL point to a business concept that would be expected to be exposed as a FHIR instance, and that instance would need to be of a FHIR resource type allowed by the reference.",
      "comment" : "When an identifier is provided in place of a reference, any system processing the reference will only be able to resolve the identifier to a reference if it understands the business context in which the identifier is used. Sometimes this is global (e.g. a national identifier) but often it is not. For this reason, none of the useful mechanisms described for working with references (e.g. chaining, includes) are possible, nor should servers be expected to be able resolve the reference. Servers may accept an identifier based reference untouched, resolve it, and/or reject it - see CapabilityStatement.rest.resource.referencePolicy. \n\nWhen both an identifier and a literal reference are provided, the literal reference is preferred. Applications processing the resource are allowed - but not required - to check that the identifier matches the literal reference\n\nApplications converting a logical reference to a literal reference may choose to leave the logical reference present, or remove it.\n\nReference is intended to point to a structure that can potentially be expressed as a FHIR resource, though there is no need for it to exist as an actual FHIR resource instance - except in as much as an application wishes to actual find the target of the reference. The content referred to be the identifier must meet the logical constraints implied by any limitations on what resource types are permitted for the reference.  For example, it would not be legitimate to send the identifier for a drug prescription if the type were Reference(Observation|DiagnosticReport).  One of the use-cases for Reference.identifier is the situation where no FHIR representation exists (where the type is Reference (Any).",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Reference.identifier",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Identifier"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : ".identifier"
      }]
    },
    {
      "id" : "MedicationStatement.subject.display",
      "extension" : [{
        "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-translatable",
        "valueBoolean" : true
      }],
      "path" : "MedicationStatement.subject.display",
      "short" : "Text alternative for the resource",
      "definition" : "Plain text narrative that identifies the resource in addition to the resource reference.",
      "comment" : "This is generally not the same as the Resource.text of the referenced resource.  The purpose is to identify what's being referenced, not to fully describe it.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Reference.display",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "string"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "path" : "MedicationStatement.context",
      "short" : "Encounter / Episode associated with MedicationStatement",
      "definition" : "The encounter or episode of care that establishes the context for this MedicationStatement.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1",
        "http://hl7.org/fhir/StructureDefinition/EpisodeOfCare|4.0.1"]
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "workflow",
        "map" : "Event.context"
      },
      {
        "identity" : "rim",
        "map" : ".inboundRelationship[typeCode=COMP].source[classCode=ENC, moodCode=EVN, code=\"type of encounter or episode\"]"
      }]
    },
    {
      "path" : "MedicationStatement.effective[x]",
      "short" : "The date/time or interval when the medication is/was/will be taken",
      "definition" : "The interval of time during which it is being asserted that the patient is/was/will be taking the medication (or was not taking, when the MedicationStatement.taken element is No).",
      "comment" : "This attribute reflects the period over which the patient consumed the medication and is expected to be populated on the majority of Medication Statements. If the medication is still being taken at the time the statement is recorded, the \"end\" date will be omitted.  The date/time attribute supports a variety of dates - year, year/month and exact date.  If something more than this is required, this should be conveyed as text.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "dateTime"
      },
      {
        "code" : "Period"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : true,
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "workflow",
        "map" : "Event.occurrence[x]"
      },
      {
        "identity" : "w5",
        "map" : "FiveWs.done[x]"
      },
      {
        "identity" : "rim",
        "map" : ".effectiveTime"
      }]
    },
    {
      "path" : "MedicationStatement.dateAsserted",
      "short" : "When the statement was asserted?",
      "definition" : "The date when the medication statement was asserted by the information source.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "dateTime"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.recorded"
      },
      {
        "identity" : "rim",
        "map" : ".participation[typeCode=AUT].time"
      }]
    },
    {
      "path" : "MedicationStatement.informationSource",
      "short" : "Person or organization that provided the information about the taking of this medication",
      "definition" : "The person or organization that provided the information about the taking of this medication. Note: Use derivedFrom when a MedicationStatement is derived from other resources, e.g. Claim or MedicationRequest.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Patient|4.0.1",
        "http://hl7.org/fhir/StructureDefinition/Practitioner|4.0.1",
        "http://hl7.org/fhir/StructureDefinition/PractitionerRole|4.0.1",
        "http://hl7.org/fhir/StructureDefinition/RelatedPerson|4.0.1",
        "http://hl7.org/fhir/StructureDefinition/Organization|4.0.1"]
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.source"
      },
      {
        "identity" : "rim",
        "map" : ".participation[typeCode=INF].role[classCode=PAT, or codes for Practioner or Related Person (if PAT is the informer, then syntax for self-reported =true)"
      }]
    },
    {
      "path" : "MedicationStatement.derivedFrom",
      "short" : "left: Additional supporting information; right: The reference to the source of the statement",
      "definition" : "Allows linking the MedicationStatement to the underlying MedicationRequest, or to other information that supports or is used to derive the MedicationStatement.",
      "comment" : "Likely references would be to MedicationRequest, MedicationDispense, Claim, Observation or QuestionnaireAnswers.  The most common use cases for deriving a MedicationStatement comes from creating a MedicationStatement from a MedicationRequest or from a lab observation or a claim.  it should be noted that the amount of information that is available varies from the type resource that you derive the MedicationStatement from.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Resource|4.0.1"]
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : ".outboundRelationship[typeCode=SPRT]/target[classCode=ACT,moodCode=EVN]"
      }]
    },
    {
      "path" : "MedicationStatement.reasonCode",
      "short" : "left: Reason for why the medication is being/was taken; right: Coded reason for use",
      "definition" : "A reason for why the medication is being/was taken.",
      "comment" : "This could be a diagnosis code. If a full condition record exists or additional detail is needed, use reasonForUseReference.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "strength" : "example",
        "description" : "A coded concept identifying why the medication is being taken.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/condition-code|4.0.1"
      },
      "mapping" : [{
        "identity" : "workflow",
        "map" : "Event.reasonCode"
      },
      {
        "identity" : "w5",
        "map" : "FiveWs.why[x]"
      },
      {
        "identity" : "rim",
        "map" : ".reasonCode"
      }]
    },
    {
      "path" : "MedicationStatement.reasonReference",
      "short" : "Condition or observation that supports why the medication is being/was taken",
      "definition" : "Condition or observation that supports why the medication is being/was taken.",
      "comment" : "This is a reference to a condition that is the reason why the medication is being/was taken.  If only a code exists, use reasonForUseCode.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Condition|4.0.1",
        "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1",
        "http://hl7.org/fhir/StructureDefinition/DiagnosticReport|4.0.1"]
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "workflow",
        "map" : "Event.reasonReference"
      },
      {
        "identity" : "w5",
        "map" : "FiveWs.why[x]"
      },
      {
        "identity" : "rim",
        "map" : ".outboundRelationship[typeCode=RSON]/target[classCode=OBS,moodCode=EVN, code=\"reason for use\"].value"
      }]
    },
    {
      "path" : "MedicationStatement.note",
      "short" : "Further information about the statement",
      "definition" : "Provides extra information about the medication statement that is not conveyed by the other attributes.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "Annotation"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "workflow",
        "map" : "Event.note"
      },
      {
        "identity" : "rim",
        "map" : ".inboundRelationship[typeCode=SUBJ]/source[classCode=OBS,moodCode=EVN,code=\"annotation\"].value"
      }]
    },
    {
      "id" : "MedicationStatement.note.id",
      "path" : "MedicationStatement.note.id",
      "representation" : ["xmlAttr"],
      "short" : "Unique id for inter-element referencing",
      "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Element.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl" : "string"
        }],
        "code" : "http://hl7.org/fhirpath/System.String"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationStatement.note.extension",
      "path" : "MedicationStatement.note.extension",
      "slicing" : {
        "discriminator" : [{
          "type" : "value",
          "path" : "url"
        }],
        "description" : "Extensions are always sliced by (at least) url",
        "rules" : "open"
      },
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Element.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])"
        }],
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationStatement.note.author[x]",
      "path" : "MedicationStatement.note.author[x]",
      "short" : "Individual responsible for the annotation",
      "definition" : "The individual responsible for making the annotation.",
      "comment" : "Organization is used when there's no need for specific attribution as to who made the comment.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Annotation.author[x]",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Practitioner|4.0.1",
        "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1",
        "http://hl7.org/fhir/StructureDefinition/RelatedPerson|4.0.1",
        "http://hl7.org/fhir/StructureDefinition/Organization|4.0.1"]
      },
      {
        "code" : "string"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "v2",
        "map" : "N/A"
      },
      {
        "identity" : "rim",
        "map" : "Act.participant[typeCode=AUT].role"
      }]
    },
    {
      "id" : "MedicationStatement.note.time",
      "path" : "MedicationStatement.note.time",
      "short" : "When the annotation was made",
      "definition" : "Indicates when this particular annotation was made.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Annotation.time",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "dateTime"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "v2",
        "map" : "N/A"
      },
      {
        "identity" : "rim",
        "map" : "Act.effectiveTime"
      }]
    },
    {
      "id" : "MedicationStatement.note.text",
      "path" : "MedicationStatement.note.text",
      "short" : "Textual note about the statement",
      "definition" : "The text of the annotation in markdown format.",
      "min" : 1,
      "max" : "1",
      "base" : {
        "path" : "Annotation.text",
        "min" : 1,
        "max" : "1"
      },
      "type" : [{
        "code" : "markdown"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "v2",
        "map" : "N/A"
      },
      {
        "identity" : "rim",
        "map" : "Act.text"
      }]
    },
    {
      "path" : "MedicationStatement.dosage",
      "short" : "left: Details of how medication is/was taken or should be taken; right: Details of how medication is/was taken or should be taken.",
      "definition" : "Indicates how the medication is/was or should be taken by the patient.",
      "comment" : "The dates included in the dosage on a Medication Statement reflect the dates for a given dose.  For example, \"from November 1, 2016 to November 3, 2016, take one tablet daily and from November 4, 2016 to November 7, 2016, take two tablets daily.\"  It is expected that this specificity may only be populated where the patient brings in their labeled container or where the Medication Statement is derived from a MedicationRequest.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "Dosage"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : true,
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "refer dosageInstruction mapping"
      }]
    },
    {
      "id" : "MedicationStatement.dosage.id",
      "path" : "MedicationStatement.dosage.id",
      "representation" : ["xmlAttr"],
      "short" : "Unique id for inter-element referencing",
      "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Element.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl" : "string"
        }],
        "code" : "http://hl7.org/fhirpath/System.String"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationStatement.dosage.extension",
      "path" : "MedicationStatement.dosage.extension",
      "slicing" : {
        "discriminator" : [{
          "type" : "value",
          "path" : "url"
        }],
        "description" : "Extensions are always sliced by (at least) url",
        "rules" : "open"
      },
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Element.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])"
        }],
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationStatement.dosage.modifierExtension",
      "path" : "MedicationStatement.dosage.modifierExtension",
      "short" : "Extensions that cannot be ignored even if unrecognized",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
      "alias" : ["extensions",
      "user content",
      "modifiers"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "BackboneElement.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])"
        }],
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : true,
      "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "MedicationStatement.dosage.sequence",
      "path" : "MedicationStatement.dosage.sequence",
      "short" : "The order of the dosage instructions",
      "definition" : "Indicates the order in which the dosage instructions should be applied or interpreted.",
      "requirements" : "If the sequence number of multiple Dosages is the same, then it is implied that the instructions are to be treated as concurrent.  If the sequence number is different, then the Dosages are intended to be sequential.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Dosage.sequence",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "integer"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "v2",
        "map" : "TQ1-1"
      },
      {
        "identity" : "rim",
        "map" : ".text"
      }]
    },
    {
      "id" : "MedicationStatement.dosage.text",
      "extension" : [{
        "extension" : [{
          "url" : "code",
          "valueCode" : "SHALL:populate-if-known"
        },
        {
          "url" : "actor",
          "valueCanonical" : "http://hl7.org/fhir/uv/ips/ActorDefinition/Creator"
        },
        {
          "url" : "http://hl7.org/fhir/tools/StructureDefinition/snapshot-source",
          "valueCanonical" : "http://hl7.org/fhir/uv/ips/StructureDefinition/MedicationStatement-uv-ips|2.0.0"
        }],
        "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
      },
      {
        "extension" : [{
          "url" : "code",
          "valueCode" : "SHALL:handle"
        },
        {
          "url" : "actor",
          "valueCanonical" : "http://hl7.org/fhir/uv/ips/ActorDefinition/Consumer"
        },
        {
          "url" : "http://hl7.org/fhir/tools/StructureDefinition/snapshot-source",
          "valueCanonical" : "http://hl7.org/fhir/uv/ips/StructureDefinition/MedicationStatement-uv-ips|2.0.0"
        }],
        "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
      },
      {
        "extension" : [{
          "url" : "code",
          "valueCode" : "SHOULD:display"
        },
        {
          "url" : "actor",
          "valueCanonical" : "http://hl7.org/fhir/uv/ips/ActorDefinition/Consumer"
        },
        {
          "url" : "http://hl7.org/fhir/tools/StructureDefinition/snapshot-source",
          "valueCanonical" : "http://hl7.org/fhir/uv/ips/StructureDefinition/MedicationStatement-uv-ips|2.0.0"
        }],
        "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
      }],
      "path" : "MedicationStatement.dosage.text",
      "short" : "Free text dosage instructions e.g. SIG",
      "definition" : "Free text dosage instructions e.g. SIG.",
      "requirements" : "Free text dosage instructions can be used for cases where the instructions are too complex to code.  The content of this attribute does not include the name or description of the medication. When coded instructions are present, the free text instructions may still be present for display to humans taking or administering the medication. It is expected that the text instructions will always be populated.  If the dosage.timing attribute is also populated, then the dosage.text should reflect the same information as the timing.  Additional information about administration or preparation of the medication should be included as text.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Dosage.text",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "string"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : true,
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "v2",
        "map" : "RXO-6; RXE-21"
      },
      {
        "identity" : "rim",
        "map" : ".text"
      }]
    },
    {
      "id" : "MedicationStatement.dosage.additionalInstruction",
      "path" : "MedicationStatement.dosage.additionalInstruction",
      "short" : "Supplemental instruction or warnings to the patient - e.g. \"with meals\", \"may cause drowsiness\"",
      "definition" : "Supplemental instructions to the patient on how to take the medication  (e.g. \"with meals\" or\"take half to one hour before food\") or warnings for the patient about the medication (e.g. \"may cause drowsiness\" or \"avoid exposure of skin to direct sunlight or sunlamps\").",
      "comment" : "Information about administration or preparation of the medication (e.g. \"infuse as rapidly as possibly via intraperitoneal port\" or \"immediately following drug x\") should be populated in dosage.text.",
      "requirements" : "Additional instruction is intended to be coded, but where no code exists, the element could include text.  For example, \"Swallow with plenty of water\" which might or might not be coded.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Dosage.additionalInstruction",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "AdditionalInstruction"
        }],
        "strength" : "example",
        "description" : "A coded concept identifying additional instructions such as \"take with water\" or \"avoid operating heavy machinery\".",
        "valueSet" : "http://hl7.org/fhir/ValueSet/additional-instruction-codes|4.0.1"
      },
      "mapping" : [{
        "identity" : "v2",
        "map" : "RXO-7"
      },
      {
        "identity" : "rim",
        "map" : ".text"
      }]
    },
    {
      "id" : "MedicationStatement.dosage.patientInstruction",
      "path" : "MedicationStatement.dosage.patientInstruction",
      "short" : "Patient or consumer oriented instructions",
      "definition" : "Instructions in terms that are understood by the patient or consumer.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Dosage.patientInstruction",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "string"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "v2",
        "map" : "RXO-7"
      },
      {
        "identity" : "rim",
        "map" : ".text"
      }]
    },
    {
      "id" : "MedicationStatement.dosage.timing",
      "extension" : [{
        "extension" : [{
          "url" : "code",
          "valueCode" : "SHALL:populate-if-known"
        },
        {
          "url" : "actor",
          "valueCanonical" : "http://hl7.org/fhir/uv/ips/ActorDefinition/Creator"
        },
        {
          "url" : "http://hl7.org/fhir/tools/StructureDefinition/snapshot-source",
          "valueCanonical" : "http://hl7.org/fhir/uv/ips/StructureDefinition/MedicationStatement-uv-ips|2.0.0"
        }],
        "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
      },
      {
        "extension" : [{
          "url" : "code",
          "valueCode" : "SHALL:handle"
        },
        {
          "url" : "actor",
          "valueCanonical" : "http://hl7.org/fhir/uv/ips/ActorDefinition/Consumer"
        },
        {
          "url" : "http://hl7.org/fhir/tools/StructureDefinition/snapshot-source",
          "valueCanonical" : "http://hl7.org/fhir/uv/ips/StructureDefinition/MedicationStatement-uv-ips|2.0.0"
        }],
        "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
      },
      {
        "extension" : [{
          "url" : "code",
          "valueCode" : "SHOULD:display"
        },
        {
          "url" : "actor",
          "valueCanonical" : "http://hl7.org/fhir/uv/ips/ActorDefinition/Consumer"
        },
        {
          "url" : "http://hl7.org/fhir/tools/StructureDefinition/snapshot-source",
          "valueCanonical" : "http://hl7.org/fhir/uv/ips/StructureDefinition/MedicationStatement-uv-ips|2.0.0"
        }],
        "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
      }],
      "path" : "MedicationStatement.dosage.timing",
      "short" : "When medication should be administered",
      "definition" : "When medication should be administered.",
      "comment" : "This attribute might not always be populated while the Dosage.text is expected to be populated.  If both are populated, then the Dosage.text should reflect the content of the Dosage.timing.",
      "requirements" : "The timing schedule for giving the medication to the patient. This  data type allows many different expressions. For example: \"Every 8 hours\"; \"Three times a day\"; \"1/2 an hour before breakfast for 10 days from 23-Dec 2011:\"; \"15 Oct 2013, 17 Oct 2013 and 1 Nov 2013\".  Sometimes, a rate can imply duration when expressed as total volume / duration (e.g.  500mL/2 hours implies a duration of 2 hours).  However, when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is needed to convey the infuse over time period.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Dosage.timing",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Timing"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : true,
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : ".effectiveTime"
      }]
    },
    {
      "id" : "MedicationStatement.dosage.asNeeded[x]",
      "path" : "MedicationStatement.dosage.asNeeded[x]",
      "short" : "Take \"as needed\" (for x)",
      "definition" : "Indicates whether the Medication is only taken when needed within a specific dosing schedule (Boolean option), or it indicates the precondition for taking the Medication (CodeableConcept).",
      "comment" : "Can express \"as needed\" without a reason by setting the Boolean = True.  In this case the CodeableConcept is not populated.  Or you can express \"as needed\" with a reason by including the CodeableConcept.  In this case the Boolean is assumed to be True.  If you set the Boolean to False, then the dose is given according to the schedule and is not \"prn\" or \"as needed\".",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Dosage.asNeeded[x]",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "boolean"
      },
      {
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "MedicationAsNeededReason"
        }],
        "strength" : "example",
        "description" : "A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose.  For example \"pain\", \"30 minutes prior to sexual intercourse\", \"on flare-up\" etc.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/medication-as-needed-reason|4.0.1"
      },
      "mapping" : [{
        "identity" : "v2",
        "map" : "TQ1-9"
      },
      {
        "identity" : "rim",
        "map" : ".outboundRelationship[typeCode=PRCN].target[classCode=OBS, moodCode=EVN, code=\"as needed\"].value=boolean or codable concept"
      }]
    },
    {
      "id" : "MedicationStatement.dosage.site",
      "path" : "MedicationStatement.dosage.site",
      "short" : "Body site to administer to",
      "definition" : "Body site to administer to.",
      "comment" : "If the use case requires attributes from the BodySite resource (e.g. to identify and track separately) then use the standard extension [bodySite](http://hl7.org/fhir/R4/extension-bodysite.html).  May be a summary code, or a reference to a very precise definition of the location, or both.",
      "requirements" : "A coded specification of the anatomic site where the medication first enters the body.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Dosage.site",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "MedicationAdministrationSite"
        }],
        "strength" : "example",
        "description" : "A coded concept describing the site location the medicine enters into or onto the body.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/approach-site-codes|4.0.1"
      },
      "mapping" : [{
        "identity" : "v2",
        "map" : "RXR-2"
      },
      {
        "identity" : "rim",
        "map" : ".approachSiteCode"
      }]
    },
    {
      "id" : "MedicationStatement.dosage.route",
      "path" : "MedicationStatement.dosage.route",
      "short" : "How drug should enter body",
      "definition" : "How drug should enter body.",
      "requirements" : "A code specifying the route or physiological path of administration of a therapeutic agent into or onto a patient's body.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Dosage.route",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "binding" : {
        "strength" : "preferred",
        "description" : "SNOMED Route Terms",
        "valueSet" : "http://hl7.org/fhir/ValueSet/route-codes",
        "additional" : [{
          "extension" : [{
            "url" : "key",
            "valueId" : "ips-medicine-route-of-administration"
          }],
          "purpose" : "candidate",
          "valueSet" : "http://hl7.org/fhir/uv/ips/ValueSet/medicine-route-of-administration",
          "documentation" : "EDQM Route Terms"
        }]
      },
      "mapping" : [{
        "identity" : "v2",
        "map" : "RXR-1"
      },
      {
        "identity" : "rim",
        "map" : ".routeCode"
      }]
    },
    {
      "id" : "MedicationStatement.dosage.method",
      "path" : "MedicationStatement.dosage.method",
      "short" : "Technique for administering medication",
      "definition" : "Technique for administering medication.",
      "comment" : "Terminologies used often pre-coordinate this term with the route and or form of administration.",
      "requirements" : "A coded value indicating the method by which the medication is introduced into or onto the body. Most commonly used for injections.  For examples, Slow Push; Deep IV.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Dosage.method",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "MedicationAdministrationMethod"
        }],
        "strength" : "example",
        "description" : "A coded concept describing the technique by which the medicine is administered.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/administration-method-codes|4.0.1"
      },
      "mapping" : [{
        "identity" : "v2",
        "map" : "RXR-4"
      },
      {
        "identity" : "rim",
        "map" : ".doseQuantity"
      }]
    },
    {
      "id" : "MedicationStatement.dosage.doseAndRate",
      "path" : "MedicationStatement.dosage.doseAndRate",
      "short" : "Amount of medication administered",
      "definition" : "The amount of medication administered.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Dosage.doseAndRate",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Element"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "v2",
        "map" : "TQ1-2"
      }]
    },
    {
      "id" : "MedicationStatement.dosage.maxDosePerPeriod",
      "path" : "MedicationStatement.dosage.maxDosePerPeriod",
      "short" : "Upper limit on medication per unit of time",
      "definition" : "Upper limit on medication per unit of time.",
      "comment" : "This is intended for use as an adjunct to the dosage when there is an upper cap.  For example \"2 tablets every 4 hours to a maximum of 8/day\".",
      "requirements" : "The maximum total quantity of a therapeutic substance that may be administered to a subject over the period of time.  For example, 1000mg in 24 hours.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Dosage.maxDosePerPeriod",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Ratio"
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "v2",
        "map" : "RXO-23, RXE-19"
      },
      {
        "identity" : "rim",
        "map" : ".maxDoseQuantity"
      }]
    },
    {
      "id" : "MedicationStatement.dosage.maxDosePerAdministration",
      "path" : "MedicationStatement.dosage.maxDosePerAdministration",
      "short" : "Upper limit on medication per administration",
      "definition" : "Upper limit on medication per administration.",
      "comment" : "This is intended for use as an adjunct to the dosage when there is an upper cap.  For example, a body surface area related dose with a maximum amount, such as 1.5 mg/m2 (maximum 2 mg) IV over 5 – 10 minutes would have doseQuantity of 1.5 mg/m2 and maxDosePerAdministration of 2 mg.",
      "requirements" : "The maximum total quantity of a therapeutic substance that may be administered to a subject per administration.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Dosage.maxDosePerAdministration",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Quantity",
        "profile" : ["http://hl7.org/fhir/StructureDefinition/SimpleQuantity|4.0.1"]
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "not supported"
      }]
    },
    {
      "id" : "MedicationStatement.dosage.maxDosePerLifetime",
      "path" : "MedicationStatement.dosage.maxDosePerLifetime",
      "short" : "Upper limit on medication per lifetime of the patient",
      "definition" : "Upper limit on medication per lifetime of the patient.",
      "requirements" : "The maximum total quantity of a therapeutic substance that may be administered per lifetime of the subject.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Dosage.maxDosePerLifetime",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Quantity",
        "profile" : ["http://hl7.org/fhir/StructureDefinition/SimpleQuantity|4.0.1"]
      }],
      "constraint" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/4.0/StructureDefinition/extension-ElementDefinition.constraint.xpath",
          "valueString" : "@value|f:*|h:div"
        }],
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "not supported"
      }]
    }]
  }
}