HL7 Europe Base and Core FHIR IG
2.0.0-gamma - qa-preview 150

HL7 Europe Base and Core FHIR IG - Downloaded Version 2.0.0-gamma See the Directory of published versions

## Resource Profile: Medication (EU core)

Official URL: http://hl7.eu/fhir/base/StructureDefinition/medication-eu-core | Version: 2.0.0-gamma
Standards status: Draft | Maturity Level: 1 | Computable Name: MedicationEuCore
Copyright/Legal: Copyright HL7 Europe. Licensed under creative commons public domain (CC0 1.0).

This profile introduces essential constraints and extensions for the Medication resource that apply across multiple use cases.

Usages:

- Refer to this Profile: Immunization (EU core), Medication (EU core), MedicationRequest (EU core), MedicationStatement (EU core) and Procedure (EU core)
- Examples for this Profile: Medication/01A-Cefuroxime1500GenericExplicit

You can also check for usages in the FHIR IG Statistics

### Formal Views of Profile Content

Description of Profiles, Differentials, Snapshots and how the different presentations work.

- Key Elements Table
- Differential Table
- Snapshot Table
- Statistics/References
- All

Name | Flags | Card. | Type | Description & Constraints Filter: Bindings Constraints Obligations
--- | --- | --- | --- | ---
Medication |  | 0..* | Medication | Definition of a Medication
implicitRules | ?!Σ | 0..1 | uri | A set of rules under which this content was created
Slices for extension |  | 0..* | Extension | Extension Slice: Unordered, Open by value:url
extension:productName |  | 0..1 | string | Current trade name (authorised name) of the medicinal product. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-productname
extension:classification |  | 0..* | CodeableConcept | Classifications of the product, e.g ATC, narcotic/psychotropic, orphan drug, etc URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-classification Binding: ProductClassification (example)
extension:sizeOfItem |  | 0..1 | Quantity | Size of one item (for example, in a pack of 5 vials, this would represent the size of 1 vial) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-sizeofitem
extension:characteristic |  | 0..* | (Complex) | Specifies other descriptive properties of the medication. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-characteristic
extension:unitOfPresentation |  | 0..1 | CodeableConcept | Unit of presentation of the product (e.g. tablet, vial, ampoule, etc) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-unitofpresentation Binding: UnitOfPresentation (example)
extension:packageType |  | 0..1 | CodeableConcept | Type of container. This information is more relevant in cases when the packaging has an impact on administration of the product (e.g. pre-filled syringe) URL: http://hl7.eu/fhir/StructureDefinition/medication-package-type Binding: eHDSI Package (example)
extension:device |  | 0..* | (Complex) | Device, typically an administration device, included in the product. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device
Slices for extension |  | 2..* | Extension | Extension Slice: Unordered, Open by value:url
extension:device |  | 1..1 | Extension | Extension
extension |  | 0..0 |  | Extension Slice: Unordered, Open by value:url
url |  | 1..1 | uri | "device"
value[x] |  | 0..1 | CodeableConcept | Value of extension Binding: eHDSI Package (example)
extension:quantity |  | 1..1 | Extension | Number of defined devices in te package
extension |  | 0..0 |  | Extension Slice: Unordered, Open by value:url
url |  | 1..1 | uri | "quantity"
url |  | 1..1 | uri | "https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device"
modifierExtension | ?! | 0..* | Extension | Extensions that cannot be ignored
identifier | Σ | 0..* | Identifier | Identifier for the medicinal product, its generic representation, or packaged product (e.g. EMA PMS ID on product or package level)
code | Σ | 0..1 | CodeableConcept | A terminology-based code for the product (e.g. SNOMED CT code) Binding: SNOMEDCTMedicationCodes (example): A coded concept that defines the type of a medication.
status | ?!Σ | 0..1 | code | active | inactive | entered-in-error Binding: Medication Status Codes (required): A coded concept defining if the medication is in active use.
manufacturer | Σ | 0..1 | Reference(Organization) | Marketing authorisation holder of the medicinal product. If the product does not have a marketing authorisation, the manufactured information may be used. It is sufficient to populate only name and optionally an identifier of the organisation.
form |  | 0..1 | CodeableConcept | powder | tablets | capsule + Binding: eHDSI Dose Form (example)
amount | Σ | 0..1 | Ratio | Amount of the medication (for example, in a package or a vial)
ingredient |  | 0..* | BackboneElement | Ingredient or a part product. For combination packs, each ingredient can be a separate manufactured item with its own ingredients, dose form, and strength
modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized
Slices for item[x] |  | 1..1 |  | The actual ingredient or content Slice: Unordered, Closed by type:$this
itemCodeableConcept |  |  | CodeableConcept |
itemReference |  |  | Reference(Substance | Medication) |
item[x]:itemReference |  | 0..1 | Reference(Medication (EU core)) | The actual ingredient or content
item[x]:itemCodeableConcept |  | 0..1 | CodeableConcept | The actual ingredient or content Binding: Medicine Active Substances - IPS (example)
Additional Bindings | Purpose
eHDSI Substance | candidate
isActive |  | 0..1 | boolean | Active ingredient indicator. By default, only active ingredients are expected - therefore, the default value is true.
strength |  | 0..1 | Ratio | Amount of substance in product (presentation or concentration strength)
Slices for extension |  |  |  | Content/Rules for all slices
extension:basisOfStrengthSubstance |  | 0..1 | CodeableConcept | Substance for which the strength is provided (this could be different from the precise active ingredient). URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-strengthsubstance Binding: SNOMEDCTSubstanceCodes (example)
Documentation for this format

#### Terminology Bindings

Path | Status | Usage | ValueSet | Version | Source
Medication.extension:device.​extension:device.value[x] | Base | example | eHDSI Package | ⏿8.1.0 | tx.hl7europe.eu
Medication.code | Base | example | SNOMED CT Medication Codes | 📍4.0.1 | FHIR Std.
Medication.status | Base | required | Medication status codes | 📍4.0.1 | FHIR Std.
Medication.form | Base | example | eHDSI Dose Form | ⏿8.1.0 | tx.hl7europe.eu
Medication.ingredient.​item[x]:itemCodeableConcept | Base | example | Medicine Active Substances - IPS | 📦2.0.0 | International Patient Summary Implementation Guide v2.0

#### Constraints

Id | Grade | Path(s) | Description | Expression
dom-2 | error | Medication | If the resource is contained in another resource, it SHALL NOT contain nested Resources | `contained.contained.empty()`
dom-3 | error | Medication | If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource | `contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()`
dom-4 | error | Medication | If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated | `contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()`
dom-5 | error | Medication | If a resource is contained in another resource, it SHALL NOT have a security label | `contained.meta.security.empty()`
dom-6 | best practice | Medication | A resource should have narrative for robust management | `text.`div`.exists()`
ele-1 | error | **ALL** elements | All FHIR elements must have a @value or children | `hasValue() or (children().count() > id.count())`
ext-1 | error | **ALL** extensions | Must have either extensions or value[x], not both | `extension.exists() != value.exists()`

This structure is derived from Medication

Name | Flags | Card. | Type | Description & Constraints Filter: Bindings Constraints Obligations
--- | --- | --- | --- | ---
Medication |  | 0..* | Medication | Definition of a Medication
Slices for extension |  | 0..* | Extension | Extension Slice: Unordered, Open by value:url
extension:productName |  | 0..1 | string | Current trade name (authorised name) of the medicinal product. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-productname
extension:classification |  | 0..* | CodeableConcept | Classifications of the product, e.g ATC, narcotic/psychotropic, orphan drug, etc URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-classification Binding: ProductClassification (example)
extension:sizeOfItem |  | 0..1 | Quantity | Size of one item (for example, in a pack of 5 vials, this would represent the size of 1 vial) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-sizeofitem
extension:characteristic |  | 0..* | (Complex) | Specifies other descriptive properties of the medication. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-characteristic
extension:unitOfPresentation |  | 0..1 | CodeableConcept | Unit of presentation of the product (e.g. tablet, vial, ampoule, etc) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-unitofpresentation Binding: UnitOfPresentation (example)
extension:packageType |  | 0..1 | CodeableConcept | Type of container. This information is more relevant in cases when the packaging has an impact on administration of the product (e.g. pre-filled syringe) URL: http://hl7.eu/fhir/StructureDefinition/medication-package-type Binding: eHDSI Package (example)
extension:device |  | 0..* | (Complex) | Device, typically an administration device, included in the product. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device
Slices for extension |  |  |  | Content/Rules for all slices
extension:device |  | 1..1 | Extension | Extension
value[x] |  | 0..1 | CodeableConcept | Value of extension Binding: eHDSI Package (example)
identifier |  | 0..* | Identifier | Identifier for the medicinal product, its generic representation, or packaged product (e.g. EMA PMS ID on product or package level)
code |  | 0..1 | CodeableConcept | A terminology-based code for the product (e.g. SNOMED CT code)
manufacturer |  | 0..1 | Reference(Organization) | Marketing authorisation holder of the medicinal product. If the product does not have a marketing authorisation, the manufactured information may be used. It is sufficient to populate only name and optionally an identifier of the organisation.
form |  | 0..1 | CodeableConcept | powder | tablets | capsule + Binding: eHDSI Dose Form (example)
amount |  | 0..1 | Ratio | Amount of the medication (for example, in a package or a vial)
ingredient |  | 0..* | BackboneElement | Ingredient or a part product. For combination packs, each ingredient can be a separate manufactured item with its own ingredients, dose form, and strength
Slices for item[x] |  | 1..1 | CodeableConcept, Reference(Substance | Medication) | The actual ingredient or content Slice: Unordered, Open by type:$this
item[x]:itemReference |  | 0..1 | Reference(Medication (EU core)) | The actual ingredient or content
item[x]:itemCodeableConcept |  | 0..1 | CodeableConcept | The actual ingredient or content Binding: Medicine Active Substances - IPS (example)
Additional Bindings | Purpose
eHDSI Substance | candidate
isActive |  | 0..1 | boolean | Active ingredient indicator. By default, only active ingredients are expected - therefore, the default value is true.
strength |  | 0..1 | Ratio | Amount of substance in product (presentation or concentration strength)
Slices for extension |  |  |  | Content/Rules for all slices
extension:basisOfStrengthSubstance |  | 0..1 | CodeableConcept | Substance for which the strength is provided (this could be different from the precise active ingredient). URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-strengthsubstance Binding: SNOMEDCTSubstanceCodes (example)
batch |  |  |  |
lotNumber |  | 0..1 | string | Lot Number
expirationDate |  | 0..1 | dateTime | Expiration Date
Documentation for this format

#### Terminology Bindings (Differential)

Path | Status | Usage | ValueSet | Version | Source
Medication.extension:device.​extension:device.value[x] | Base | example | eHDSI Package | ⏿8.1.0 | tx.hl7europe.eu
Medication.form | Base | example | eHDSI Dose Form | ⏿8.1.0 | tx.hl7europe.eu
Medication.ingredient.​item[x]:itemCodeableConcept | Base | example | Medicine Active Substances - IPS | 📦2.0.0 | International Patient Summary Implementation Guide v2.0

Name | Flags | Card. | Type | Description & Constraints Filter: Bindings Constraints Obligations
--- | --- | --- | --- | ---
Medication |  | 0..* | Medication | Definition of a Medication
id | Σ | 0..1 | id | Logical id of this artifact
meta | Σ | 0..1 | Meta | Metadata about the resource
implicitRules | ?!Σ | 0..1 | uri | A set of rules under which this content was created
language |  | 0..1 | code | Language of the resource content Binding: CommonLanguages (preferred): A human language.
Additional Bindings | Purpose
AllLanguages | Max Binding
text |  | 0..1 | Narrative | Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements
contained |  | 0..* | Resource | Contained, inline Resources
Slices for extension |  | 0..* | Extension | Extension Slice: Unordered, Open by value:url
extension:productName |  | 0..1 | string | Current trade name (authorised name) of the medicinal product. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-productname
extension:classification |  | 0..* | CodeableConcept | Classifications of the product, e.g ATC, narcotic/psychotropic, orphan drug, etc URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-classification Binding: ProductClassification (example)
extension:sizeOfItem |  | 0..1 | Quantity | Size of one item (for example, in a pack of 5 vials, this would represent the size of 1 vial) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-sizeofitem
extension:characteristic |  | 0..* | (Complex) | Specifies other descriptive properties of the medication. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-characteristic
extension:unitOfPresentation |  | 0..1 | CodeableConcept | Unit of presentation of the product (e.g. tablet, vial, ampoule, etc) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-unitofpresentation Binding: UnitOfPresentation (example)
extension:packageType |  | 0..1 | CodeableConcept | Type of container. This information is more relevant in cases when the packaging has an impact on administration of the product (e.g. pre-filled syringe) URL: http://hl7.eu/fhir/StructureDefinition/medication-package-type Binding: eHDSI Package (example)
extension:device |  | 0..* | (Complex) | Device, typically an administration device, included in the product. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device
id |  | 0..1 | string | Unique id for inter-element referencing
Slices for extension |  | 2..* | Extension | Extension Slice: Unordered, Open by value:url
extension:device |  | 1..1 | Extension | Extension
id |  | 0..1 | string | Unique id for inter-element referencing
extension |  | 0..0 |  | Extension Slice: Unordered, Open by value:url
url |  | 1..1 | uri | "device"
value[x] |  | 0..1 | CodeableConcept | Value of extension Binding: eHDSI Package (example)
extension:quantity |  | 1..1 | Extension | Number of defined devices in te package
id |  | 0..1 | string | Unique id for inter-element referencing
extension |  | 0..0 |  | Extension Slice: Unordered, Open by value:url
url |  | 1..1 | uri | "quantity"
value[x] |  | 0..1 | Quantity | Value of extension
url |  | 1..1 | uri | "https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device"
modifierExtension | ?! | 0..* | Extension | Extensions that cannot be ignored
identifier | Σ | 0..* | Identifier | Identifier for the medicinal product, its generic representation, or packaged product (e.g. EMA PMS ID on product or package level)
code | Σ | 0..1 | CodeableConcept | A terminology-based code for the product (e.g. SNOMED CT code) Binding: SNOMEDCTMedicationCodes (example): A coded concept that defines the type of a medication.
status | ?!Σ | 0..1 | code | active | inactive | entered-in-error Binding: Medication Status Codes (required): A coded concept defining if the medication is in active use.
manufacturer | Σ | 0..1 | Reference(Organization) | Marketing authorisation holder of the medicinal product. If the product does not have a marketing authorisation, the manufactured information may be used. It is sufficient to populate only name and optionally an identifier of the organisation.
form |  | 0..1 | CodeableConcept | powder | tablets | capsule + Binding: eHDSI Dose Form (example)
amount | Σ | 0..1 | Ratio | Amount of the medication (for example, in a package or a vial)
ingredient |  | 0..* | BackboneElement | Ingredient or a part product. For combination packs, each ingredient can be a separate manufactured item with its own ingredients, dose form, and strength
id |  | 0..1 | string | Unique id for inter-element referencing
extension |  | 0..* | Extension | Additional content defined by implementations
modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized
Slices for item[x] |  | 1..1 |  | The actual ingredient or content Slice: Unordered, Closed by type:$this
itemCodeableConcept |  |  | CodeableConcept |
itemReference |  |  | Reference(Substance | Medication) |
item[x]:itemReference |  | 0..1 | Reference(Medication (EU core)) | The actual ingredient or content
item[x]:itemCodeableConcept |  | 0..1 | CodeableConcept | The actual ingredient or content Binding: Medicine Active Substances - IPS (example)
Additional Bindings | Purpose
eHDSI Substance | candidate
isActive |  | 0..1 | boolean | Active ingredient indicator. By default, only active ingredients are expected - therefore, the default value is true.
strength |  | 0..1 | Ratio | Amount of substance in product (presentation or concentration strength)
id |  | 0..1 | string | Unique id for inter-element referencing
Slices for extension |  | 0..* | Extension | Additional content defined by implementations Slice: Unordered, Open by value:url
extension:basisOfStrengthSubstance |  | 0..1 | CodeableConcept | Substance for which the strength is provided (this could be different from the precise active ingredient). URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-strengthsubstance Binding: SNOMEDCTSubstanceCodes (example)
numerator | Σ | 0..1 | Quantity | Numerator value
denominator | Σ | 0..1 | Quantity | Denominator value
batch |  | 0..1 | BackboneElement | Details about packaged medications
id |  | 0..1 | string | Unique id for inter-element referencing
extension |  | 0..* | Extension | Additional content defined by implementations
modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized
lotNumber |  | 0..1 | string | Lot Number
expirationDate |  | 0..1 | dateTime | Expiration Date
Documentation for this format

#### Terminology Bindings

Path | Status | Usage | ValueSet | Version | Source
Medication.language | Base | preferred | Common Languages | 📍4.0.1 | FHIR Std.
Medication.extension:device.​extension:device.value[x] | Base | example | eHDSI Package | ⏿8.1.0 | tx.hl7europe.eu
Medication.code | Base | example | SNOMED CT Medication Codes | 📍4.0.1 | FHIR Std.
Medication.status | Base | required | Medication status codes | 📍4.0.1 | FHIR Std.
Medication.form | Base | example | eHDSI Dose Form | ⏿8.1.0 | tx.hl7europe.eu
Medication.ingredient.​item[x]:itemCodeableConcept | Base | example | Medicine Active Substances - IPS | 📦2.0.0 | International Patient Summary Implementation Guide v2.0

#### Constraints

Id | Grade | Path(s) | Description | Expression
dom-2 | error | Medication | If the resource is contained in another resource, it SHALL NOT contain nested Resources | `contained.contained.empty()`
dom-3 | error | Medication | If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource | `contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()`
dom-4 | error | Medication | If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated | `contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()`
dom-5 | error | Medication | If a resource is contained in another resource, it SHALL NOT have a security label | `contained.meta.security.empty()`
dom-6 | best practice | Medication | A resource should have narrative for robust management | `text.`div`.exists()`
ele-1 | error | **ALL** elements | All FHIR elements must have a @value or children | `hasValue() or (children().count() > id.count())`
ext-1 | error | **ALL** extensions | Must have either extensions or value[x], not both | `extension.exists() != value.exists()`

This structure is derived from Medication

Summary

Structures

This structure refers to these other structures:

- Medication (EU core) (http://hl7.eu/fhir/base/StructureDefinition/medication-eu-core)

Extensions

This structure refers to these extensions:

- https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-productname
- https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-classification
- https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-sizeofitem
- https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-characteristic
- https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-unitofpresentation
- http://hl7.eu/fhir/StructureDefinition/medication-package-type
- https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device
- https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-strengthsubstance

Slices

This structure defines the following Slices:

- The element 1 is sliced based on the value of Medication.ingredient.item[x]

Maturity: 1

Key Elements View

Name | Flags | Card. | Type | Description & Constraints Filter: Bindings Constraints Obligations
--- | --- | --- | --- | ---
Medication |  | 0..* | Medication | Definition of a Medication
implicitRules | ?!Σ | 0..1 | uri | A set of rules under which this content was created
Slices for extension |  | 0..* | Extension | Extension Slice: Unordered, Open by value:url
extension:productName |  | 0..1 | string | Current trade name (authorised name) of the medicinal product. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-productname
extension:classification |  | 0..* | CodeableConcept | Classifications of the product, e.g ATC, narcotic/psychotropic, orphan drug, etc URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-classification Binding: ProductClassification (example)
extension:sizeOfItem |  | 0..1 | Quantity | Size of one item (for example, in a pack of 5 vials, this would represent the size of 1 vial) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-sizeofitem
extension:characteristic |  | 0..* | (Complex) | Specifies other descriptive properties of the medication. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-characteristic
extension:unitOfPresentation |  | 0..1 | CodeableConcept | Unit of presentation of the product (e.g. tablet, vial, ampoule, etc) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-unitofpresentation Binding: UnitOfPresentation (example)
extension:packageType |  | 0..1 | CodeableConcept | Type of container. This information is more relevant in cases when the packaging has an impact on administration of the product (e.g. pre-filled syringe) URL: http://hl7.eu/fhir/StructureDefinition/medication-package-type Binding: eHDSI Package (example)
extension:device |  | 0..* | (Complex) | Device, typically an administration device, included in the product. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device
Slices for extension |  | 2..* | Extension | Extension Slice: Unordered, Open by value:url
extension:device |  | 1..1 | Extension | Extension
extension |  | 0..0 |  | Extension Slice: Unordered, Open by value:url
url |  | 1..1 | uri | "device"
value[x] |  | 0..1 | CodeableConcept | Value of extension Binding: eHDSI Package (example)
extension:quantity |  | 1..1 | Extension | Number of defined devices in te package
extension |  | 0..0 |  | Extension Slice: Unordered, Open by value:url
url |  | 1..1 | uri | "quantity"
url |  | 1..1 | uri | "https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device"
modifierExtension | ?! | 0..* | Extension | Extensions that cannot be ignored
identifier | Σ | 0..* | Identifier | Identifier for the medicinal product, its generic representation, or packaged product (e.g. EMA PMS ID on product or package level)
code | Σ | 0..1 | CodeableConcept | A terminology-based code for the product (e.g. SNOMED CT code) Binding: SNOMEDCTMedicationCodes (example): A coded concept that defines the type of a medication.
status | ?!Σ | 0..1 | code | active | inactive | entered-in-error Binding: Medication Status Codes (required): A coded concept defining if the medication is in active use.
manufacturer | Σ | 0..1 | Reference(Organization) | Marketing authorisation holder of the medicinal product. If the product does not have a marketing authorisation, the manufactured information may be used. It is sufficient to populate only name and optionally an identifier of the organisation.
form |  | 0..1 | CodeableConcept | powder | tablets | capsule + Binding: eHDSI Dose Form (example)
amount | Σ | 0..1 | Ratio | Amount of the medication (for example, in a package or a vial)
ingredient |  | 0..* | BackboneElement | Ingredient or a part product. For combination packs, each ingredient can be a separate manufactured item with its own ingredients, dose form, and strength
modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized
Slices for item[x] |  | 1..1 |  | The actual ingredient or content Slice: Unordered, Closed by type:$this
itemCodeableConcept |  |  | CodeableConcept |
itemReference |  |  | Reference(Substance | Medication) |
item[x]:itemReference |  | 0..1 | Reference(Medication (EU core)) | The actual ingredient or content
item[x]:itemCodeableConcept |  | 0..1 | CodeableConcept | The actual ingredient or content Binding: Medicine Active Substances - IPS (example)
Additional Bindings | Purpose
eHDSI Substance | candidate
isActive |  | 0..1 | boolean | Active ingredient indicator. By default, only active ingredients are expected - therefore, the default value is true.
strength |  | 0..1 | Ratio | Amount of substance in product (presentation or concentration strength)
Slices for extension |  |  |  | Content/Rules for all slices
extension:basisOfStrengthSubstance |  | 0..1 | CodeableConcept | Substance for which the strength is provided (this could be different from the precise active ingredient). URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-strengthsubstance Binding: SNOMEDCTSubstanceCodes (example)
Documentation for this format

#### Terminology Bindings

Path | Status | Usage | ValueSet | Version | Source
Medication.extension:device.​extension:device.value[x] | Base | example | eHDSI Package | ⏿8.1.0 | tx.hl7europe.eu
Medication.code | Base | example | SNOMED CT Medication Codes | 📍4.0.1 | FHIR Std.
Medication.status | Base | required | Medication status codes | 📍4.0.1 | FHIR Std.
Medication.form | Base | example | eHDSI Dose Form | ⏿8.1.0 | tx.hl7europe.eu
Medication.ingredient.​item[x]:itemCodeableConcept | Base | example | Medicine Active Substances - IPS | 📦2.0.0 | International Patient Summary Implementation Guide v2.0

#### Constraints

Id | Grade | Path(s) | Description | Expression
dom-2 | error | Medication | If the resource is contained in another resource, it SHALL NOT contain nested Resources | `contained.contained.empty()`
dom-3 | error | Medication | If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource | `contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()`
dom-4 | error | Medication | If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated | `contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()`
dom-5 | error | Medication | If a resource is contained in another resource, it SHALL NOT have a security label | `contained.meta.security.empty()`
dom-6 | best practice | Medication | A resource should have narrative for robust management | `text.`div`.exists()`
ele-1 | error | **ALL** elements | All FHIR elements must have a @value or children | `hasValue() or (children().count() > id.count())`
ext-1 | error | **ALL** extensions | Must have either extensions or value[x], not both | `extension.exists() != value.exists()`

Differential View

This structure is derived from Medication

Name | Flags | Card. | Type | Description & Constraints Filter: Bindings Constraints Obligations
--- | --- | --- | --- | ---
Medication |  | 0..* | Medication | Definition of a Medication
Slices for extension |  | 0..* | Extension | Extension Slice: Unordered, Open by value:url
extension:productName |  | 0..1 | string | Current trade name (authorised name) of the medicinal product. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-productname
extension:classification |  | 0..* | CodeableConcept | Classifications of the product, e.g ATC, narcotic/psychotropic, orphan drug, etc URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-classification Binding: ProductClassification (example)
extension:sizeOfItem |  | 0..1 | Quantity | Size of one item (for example, in a pack of 5 vials, this would represent the size of 1 vial) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-sizeofitem
extension:characteristic |  | 0..* | (Complex) | Specifies other descriptive properties of the medication. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-characteristic
extension:unitOfPresentation |  | 0..1 | CodeableConcept | Unit of presentation of the product (e.g. tablet, vial, ampoule, etc) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-unitofpresentation Binding: UnitOfPresentation (example)
extension:packageType |  | 0..1 | CodeableConcept | Type of container. This information is more relevant in cases when the packaging has an impact on administration of the product (e.g. pre-filled syringe) URL: http://hl7.eu/fhir/StructureDefinition/medication-package-type Binding: eHDSI Package (example)
extension:device |  | 0..* | (Complex) | Device, typically an administration device, included in the product. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device
Slices for extension |  |  |  | Content/Rules for all slices
extension:device |  | 1..1 | Extension | Extension
value[x] |  | 0..1 | CodeableConcept | Value of extension Binding: eHDSI Package (example)
identifier |  | 0..* | Identifier | Identifier for the medicinal product, its generic representation, or packaged product (e.g. EMA PMS ID on product or package level)
code |  | 0..1 | CodeableConcept | A terminology-based code for the product (e.g. SNOMED CT code)
manufacturer |  | 0..1 | Reference(Organization) | Marketing authorisation holder of the medicinal product. If the product does not have a marketing authorisation, the manufactured information may be used. It is sufficient to populate only name and optionally an identifier of the organisation.
form |  | 0..1 | CodeableConcept | powder | tablets | capsule + Binding: eHDSI Dose Form (example)
amount |  | 0..1 | Ratio | Amount of the medication (for example, in a package or a vial)
ingredient |  | 0..* | BackboneElement | Ingredient or a part product. For combination packs, each ingredient can be a separate manufactured item with its own ingredients, dose form, and strength
Slices for item[x] |  | 1..1 | CodeableConcept, Reference(Substance | Medication) | The actual ingredient or content Slice: Unordered, Open by type:$this
item[x]:itemReference |  | 0..1 | Reference(Medication (EU core)) | The actual ingredient or content
item[x]:itemCodeableConcept |  | 0..1 | CodeableConcept | The actual ingredient or content Binding: Medicine Active Substances - IPS (example)
Additional Bindings | Purpose
eHDSI Substance | candidate
isActive |  | 0..1 | boolean | Active ingredient indicator. By default, only active ingredients are expected - therefore, the default value is true.
strength |  | 0..1 | Ratio | Amount of substance in product (presentation or concentration strength)
Slices for extension |  |  |  | Content/Rules for all slices
extension:basisOfStrengthSubstance |  | 0..1 | CodeableConcept | Substance for which the strength is provided (this could be different from the precise active ingredient). URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-strengthsubstance Binding: SNOMEDCTSubstanceCodes (example)
batch |  |  |  |
lotNumber |  | 0..1 | string | Lot Number
expirationDate |  | 0..1 | dateTime | Expiration Date
Documentation for this format

#### Terminology Bindings (Differential)

Path | Status | Usage | ValueSet | Version | Source
Medication.extension:device.​extension:device.value[x] | Base | example | eHDSI Package | ⏿8.1.0 | tx.hl7europe.eu
Medication.form | Base | example | eHDSI Dose Form | ⏿8.1.0 | tx.hl7europe.eu
Medication.ingredient.​item[x]:itemCodeableConcept | Base | example | Medicine Active Substances - IPS | 📦2.0.0 | International Patient Summary Implementation Guide v2.0

Snapshot View

Name | Flags | Card. | Type | Description & Constraints Filter: Bindings Constraints Obligations
--- | --- | --- | --- | ---
Medication |  | 0..* | Medication | Definition of a Medication
id | Σ | 0..1 | id | Logical id of this artifact
meta | Σ | 0..1 | Meta | Metadata about the resource
implicitRules | ?!Σ | 0..1 | uri | A set of rules under which this content was created
language |  | 0..1 | code | Language of the resource content Binding: CommonLanguages (preferred): A human language.
Additional Bindings | Purpose
AllLanguages | Max Binding
text |  | 0..1 | Narrative | Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements
contained |  | 0..* | Resource | Contained, inline Resources
Slices for extension |  | 0..* | Extension | Extension Slice: Unordered, Open by value:url
extension:productName |  | 0..1 | string | Current trade name (authorised name) of the medicinal product. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-productname
extension:classification |  | 0..* | CodeableConcept | Classifications of the product, e.g ATC, narcotic/psychotropic, orphan drug, etc URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-classification Binding: ProductClassification (example)
extension:sizeOfItem |  | 0..1 | Quantity | Size of one item (for example, in a pack of 5 vials, this would represent the size of 1 vial) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-sizeofitem
extension:characteristic |  | 0..* | (Complex) | Specifies other descriptive properties of the medication. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-characteristic
extension:unitOfPresentation |  | 0..1 | CodeableConcept | Unit of presentation of the product (e.g. tablet, vial, ampoule, etc) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-unitofpresentation Binding: UnitOfPresentation (example)
extension:packageType |  | 0..1 | CodeableConcept | Type of container. This information is more relevant in cases when the packaging has an impact on administration of the product (e.g. pre-filled syringe) URL: http://hl7.eu/fhir/StructureDefinition/medication-package-type Binding: eHDSI Package (example)
extension:device |  | 0..* | (Complex) | Device, typically an administration device, included in the product. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device
id |  | 0..1 | string | Unique id for inter-element referencing
Slices for extension |  | 2..* | Extension | Extension Slice: Unordered, Open by value:url
extension:device |  | 1..1 | Extension | Extension
id |  | 0..1 | string | Unique id for inter-element referencing
extension |  | 0..0 |  | Extension Slice: Unordered, Open by value:url
url |  | 1..1 | uri | "device"
value[x] |  | 0..1 | CodeableConcept | Value of extension Binding: eHDSI Package (example)
extension:quantity |  | 1..1 | Extension | Number of defined devices in te package
id |  | 0..1 | string | Unique id for inter-element referencing
extension |  | 0..0 |  | Extension Slice: Unordered, Open by value:url
url |  | 1..1 | uri | "quantity"
value[x] |  | 0..1 | Quantity | Value of extension
url |  | 1..1 | uri | "https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device"
modifierExtension | ?! | 0..* | Extension | Extensions that cannot be ignored
identifier | Σ | 0..* | Identifier | Identifier for the medicinal product, its generic representation, or packaged product (e.g. EMA PMS ID on product or package level)
code | Σ | 0..1 | CodeableConcept | A terminology-based code for the product (e.g. SNOMED CT code) Binding: SNOMEDCTMedicationCodes (example): A coded concept that defines the type of a medication.
status | ?!Σ | 0..1 | code | active | inactive | entered-in-error Binding: Medication Status Codes (required): A coded concept defining if the medication is in active use.
manufacturer | Σ | 0..1 | Reference(Organization) | Marketing authorisation holder of the medicinal product. If the product does not have a marketing authorisation, the manufactured information may be used. It is sufficient to populate only name and optionally an identifier of the organisation.
form |  | 0..1 | CodeableConcept | powder | tablets | capsule + Binding: eHDSI Dose Form (example)
amount | Σ | 0..1 | Ratio | Amount of the medication (for example, in a package or a vial)
ingredient |  | 0..* | BackboneElement | Ingredient or a part product. For combination packs, each ingredient can be a separate manufactured item with its own ingredients, dose form, and strength
id |  | 0..1 | string | Unique id for inter-element referencing
extension |  | 0..* | Extension | Additional content defined by implementations
modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized
Slices for item[x] |  | 1..1 |  | The actual ingredient or content Slice: Unordered, Closed by type:$this
itemCodeableConcept |  |  | CodeableConcept |
itemReference |  |  | Reference(Substance | Medication) |
item[x]:itemReference |  | 0..1 | Reference(Medication (EU core)) | The actual ingredient or content
item[x]:itemCodeableConcept |  | 0..1 | CodeableConcept | The actual ingredient or content Binding: Medicine Active Substances - IPS (example)
Additional Bindings | Purpose
eHDSI Substance | candidate
isActive |  | 0..1 | boolean | Active ingredient indicator. By default, only active ingredients are expected - therefore, the default value is true.
strength |  | 0..1 | Ratio | Amount of substance in product (presentation or concentration strength)
id |  | 0..1 | string | Unique id for inter-element referencing
Slices for extension |  | 0..* | Extension | Additional content defined by implementations Slice: Unordered, Open by value:url
extension:basisOfStrengthSubstance |  | 0..1 | CodeableConcept | Substance for which the strength is provided (this could be different from the precise active ingredient). URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-strengthsubstance Binding: SNOMEDCTSubstanceCodes (example)
numerator | Σ | 0..1 | Quantity | Numerator value
denominator | Σ | 0..1 | Quantity | Denominator value
batch |  | 0..1 | BackboneElement | Details about packaged medications
id |  | 0..1 | string | Unique id for inter-element referencing
extension |  | 0..* | Extension | Additional content defined by implementations
modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized
lotNumber |  | 0..1 | string | Lot Number
expirationDate |  | 0..1 | dateTime | Expiration Date
Documentation for this format

#### Terminology Bindings

Path | Status | Usage | ValueSet | Version | Source
Medication.language | Base | preferred | Common Languages | 📍4.0.1 | FHIR Std.
Medication.extension:device.​extension:device.value[x] | Base | example | eHDSI Package | ⏿8.1.0 | tx.hl7europe.eu
Medication.code | Base | example | SNOMED CT Medication Codes | 📍4.0.1 | FHIR Std.
Medication.status | Base | required | Medication status codes | 📍4.0.1 | FHIR Std.
Medication.form | Base | example | eHDSI Dose Form | ⏿8.1.0 | tx.hl7europe.eu
Medication.ingredient.​item[x]:itemCodeableConcept | Base | example | Medicine Active Substances - IPS | 📦2.0.0 | International Patient Summary Implementation Guide v2.0

#### Constraints

Id | Grade | Path(s) | Description | Expression
dom-2 | error | Medication | If the resource is contained in another resource, it SHALL NOT contain nested Resources | `contained.contained.empty()`
dom-3 | error | Medication | If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource | `contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()`
dom-4 | error | Medication | If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated | `contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()`
dom-5 | error | Medication | If a resource is contained in another resource, it SHALL NOT have a security label | `contained.meta.security.empty()`
dom-6 | best practice | Medication | A resource should have narrative for robust management | `text.`div`.exists()`
ele-1 | error | **ALL** elements | All FHIR elements must have a @value or children | `hasValue() or (children().count() > id.count())`
ext-1 | error | **ALL** extensions | Must have either extensions or value[x], not both | `extension.exists() != value.exists()`

This structure is derived from Medication

Summary

Structures

This structure refers to these other structures:

- Medication (EU core) (http://hl7.eu/fhir/base/StructureDefinition/medication-eu-core)

Extensions

This structure refers to these extensions:

- https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-productname
- https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-classification
- https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-sizeofitem
- https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-characteristic
- https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-unitofpresentation
- http://hl7.eu/fhir/StructureDefinition/medication-package-type
- https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device
- https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-strengthsubstance

Slices

This structure defines the following Slices:

- The element 1 is sliced based on the value of Medication.ingredient.item[x]

Maturity: 1

Other representations of profile: CSV, Excel, Schematron