HL7 Europe Common Cancer Model
1.0.0-ballot - ballot 150

HL7 Europe Common Cancer Model - Local Development build (v1.0.0-ballot) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions

## Logical Model: SystemicTreatment - JSON Profile

Active as of 2026-06-14

JSON representation of the SystemicTreatment logical model.

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    {
      "resourceType" : "StructureDefinition",
      "id" : "SystemicTreatment",
      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: StructureDefinition SystemicTreatment</b></p><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" style=\"border: 0px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;\"><tr style=\"border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top\"><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"The logical name of the element\">Name</a></th><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Information about the use of the element\">Flags</a></th><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Minimum and Maximum # of times the element can appear in the instance\">Card.</a></th><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px; width: 100px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Reference to the type of the element\">Type</a></th><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Additional information about the element\">Description &amp; Constraints</a><span style=\"float: right\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Legend for this format\"><img src=\"data:image/png;base64, \" alt=\"doco\" style=\"background-color: inherit\"/></a></span></th></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-SystemicTreatment-definitions.html#SystemicTreatment\" title=\"Logical model representing a systemic anti-cancer treatment episode delivered to the patient, either at diagnosis or following disease progression. Derived from Cancer_Common_Logical_Model_20260521.xlsx (sheet SystemicTreatment).\">SystemicTreatment</a><a name=\"SystemicTreatment\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"padding-left: 3px; padding-right: 3px; border: 1px maroon solid; font-weight: bold; color: #301212; background-color: #fdf4f4;; padding-left: 3px; padding-right: 3px; border: 1px maroon solid; font-weight: bold; color: #301212; background-color: #fdf4f4;\" href=\"http://hl7.org/fhir/R4/conformance-rules.html#constraints\" title=\"This element has or is affected by constraints ( st-1, st-2 )\">C</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">0</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">*</span></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://build.fhir.org/types.html#Base\">Base</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">SystemicTreatment<br/><span style=\"font-weight:bold\">Instances of this logical model can be the target of a Reference</span><br class=\"constraint\"/><span title=\"null\" class=\"constraint\">Constraints: </span><span style=\"font-weight:bold\" title=\"If ongoing is true, endDate must not be present; if endDate is not present, ongoing must be true.\" class=\"constraint\">st-1</span><span title=\"null\" class=\"constraint\">, </span><span style=\"font-weight:bold\" title=\"If endDate is present, it should be greater than or equal to startDate.\" class=\"constraint\">st-2</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_reference.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Reference to another Resource\" class=\"hierarchy\"/> <a href=\"StructureDefinition-SystemicTreatment-definitions.html#SystemicTreatment.subject\" title=\"Reference to the patient (subject) receiving systemic treatment.\">subject</a><a name=\"SystemicTreatment.subject\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/references.html\">Reference</a>(<a href=\"StructureDefinition-CancerPatient.html\">Cancer Patient</a>)</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Subject</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_reference.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Reference to another Resource\" class=\"hierarchy\"/> <a href=\"StructureDefinition-SystemicTreatment-definitions.html#SystemicTreatment.cancerConditionAtDiagnosisReference\" title=\"Reference to the cancer condition at diagnosis targeted by systemic treatment.\">cancerConditionAtDiagnosisReference</a><a name=\"SystemicTreatment.cancerConditionAtDiagnosisReference\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/references.html\">Reference</a>(<a href=\"StructureDefinition-CancerConditionAtDiagnosis.html\">CancerConditionAtDiagnosis</a>)</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">CancerConditionAtDiagnosisReference</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_reference.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Reference to another Resource\" class=\"hierarchy\"/> <a href=\"StructureDefinition-SystemicTreatment-definitions.html#SystemicTreatment.clinicalCancerProgressionReference\" title=\"Reference to the clinical progression event, if treatment is delivered in response to progression.\">clinicalCancerProgressionReference</a><a name=\"SystemicTreatment.clinicalCancerProgressionReference\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/references.html\">Reference</a>(<a href=\"StructureDefinition-ClinicalCancerProgression.html\">ClinicalCancerProgression</a>)</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">ClinicalCancerProgresionReference</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-SystemicTreatment-definitions.html#SystemicTreatment.intent\" title=\"Treatment intent (Definitive/curative vs Palliative).\">intent</a><a name=\"SystemicTreatment.intent\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Intent</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-SystemicTreatment-definitions.html#SystemicTreatment.type\" title=\"Category of systemic treatment (e.g. chemotherapy, immunotherapy, targeted therapy, hormonal therapy).\">type</a><a name=\"SystemicTreatment.type\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Type</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-SystemicTreatment-definitions.html#SystemicTreatment.startDate\" title=\"Start date of the systemic treatment course.\">startDate</a><a name=\"SystemicTreatment.startDate\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#dateTime\">dateTime</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">StartDate</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-SystemicTreatment-definitions.html#SystemicTreatment.endDate\" title=\"End date of the systemic treatment course (may be missing while ongoing).\">endDate</a><a name=\"SystemicTreatment.endDate\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#dateTime\">dateTime</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">EndDate</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-SystemicTreatment-definitions.html#SystemicTreatment.ongoing\" title=\"Indicates that the treatment is ongoing when EndDate is not available.\">ongoing</a><a name=\"SystemicTreatment.ongoing\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Ongoing</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck00.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-SystemicTreatment-definitions.html#SystemicTreatment.setting\" title=\"Strategic timing/setting of systemic treatment (e.g. neoadjuvant, adjuvant, concomitant, alone).\">setting</a><a name=\"SystemicTreatment.setting\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Setting</td></tr>\r\n<tr><td colspan=\"5\" class=\"hierarchy\"><br/><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Legend for this format\"><img src=\"data:image/png;base64, \" alt=\"doco\" style=\"background-color: inherit\"/> Documentation for this format</a></td></tr></table></div>"
      },
      "extension" : [
        {
          "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-type-characteristics",
          "valueCode" : "can-be-target"
        }
      ],
      "url" : "http://hl7.eu/fhir/cancer-common/StructureDefinition/SystemicTreatment",
      "version" : "1.0.0-ballot",
      "name" : "SystemicTreatment",
      "title" : "SystemicTreatment",
      "status" : "active",
      "date" : "2026-06-14T12:51:40+02:00",
      "publisher" : "HL7 Europe",
      "contact" : [
        {
          "name" : "HL7 Europe",
          "telecom" : [
            {
              "system" : "url",
              "value" : "http://hl7.eu"
            }
          ]
        }
      ],
      "description" : "Logical model representing a systemic anti-cancer treatment episode delivered to the patient, either at diagnosis or following disease progression. Derived from Cancer_Common_Logical_Model_20260521.xlsx (sheet SystemicTreatment).",
      "jurisdiction" : [
        {
          "coding" : [
            {
              "system" : "http://unstats.un.org/unsd/methods/m49/m49.htm",
              "code" : "150",
              "display" : "Europe"
            }
          ]
        }
      ],
      "copyright" : "HL7 Europe Copyright. Licensed under Common Creative License (CC0 1.0). Details at [Copyright](copyright.html).",
      "fhirVersion" : "4.0.1",
      "kind" : "logical",
      "abstract" : false,
      "type" : "http://hl7.eu/fhir/cancer-common/StructureDefinition/SystemicTreatment",
      "baseDefinition" : "http://hl7.org/fhir/StructureDefinition/Base",
      "derivation" : "specialization",
      "snapshot" : {
        "extension" : [
          {
            "url" : "http://hl7.org/fhir/tools/StructureDefinition/snapshot-base-version",
            "valueString" : "4.0.1"
          }
        ],
        "element" : [
          {
            "id" : "SystemicTreatment",
            "path" : "SystemicTreatment",
            "short" : "SystemicTreatment",
            "definition" : "Logical model representing a systemic anti-cancer treatment episode delivered to the patient, either at diagnosis or following disease progression. Derived from Cancer_Common_Logical_Model_20260521.xlsx (sheet SystemicTreatment).",
            "min" : 0,
            "max" : "*",
            "base" : {
              "path" : "Base",
              "min" : 0,
              "max" : "*"
            },
            "constraint" : [
              {
                "key" : "st-1",
                "severity" : "error",
                "human" : "If ongoing is true, endDate must not be present; if endDate is not present, ongoing must be true.",
                "expression" : "((ongoing = true) implies endDate.empty()) and (endDate.exists() implies (ongoing.exists().not() or ongoing = false))",
                "source" : "http://hl7.eu/fhir/cancer-common/StructureDefinition/SystemicTreatment"
              },
              {
                "key" : "st-2",
                "severity" : "warning",
                "human" : "If endDate is present, it should be greater than or equal to startDate.",
                "expression" : "endDate.empty() or endDate > startDate",
                "source" : "http://hl7.eu/fhir/cancer-common/StructureDefinition/SystemicTreatment"
              }
            ],
            "isModifier" : false
          },
          {
            "id" : "SystemicTreatment.subject",
            "path" : "SystemicTreatment.subject",
            "short" : "Subject",
            "definition" : "Reference to the patient (subject) receiving systemic treatment.",
            "min" : 1,
            "max" : "1",
            "base" : {
              "path" : "SystemicTreatment.subject",
              "min" : 1,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "Reference",
                "targetProfile" : [
                  🔗 "http://hl7.eu/fhir/cancer-common/StructureDefinition/CancerPatient"
                ]
              }
            ]
          },
          {
            "id" : "SystemicTreatment.cancerConditionAtDiagnosisReference",
            "path" : "SystemicTreatment.cancerConditionAtDiagnosisReference",
            "short" : "CancerConditionAtDiagnosisReference",
            "definition" : "Reference to the cancer condition at diagnosis targeted by systemic treatment.",
            "min" : 1,
            "max" : "1",
            "base" : {
              "path" : "SystemicTreatment.cancerConditionAtDiagnosisReference",
              "min" : 1,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "Reference",
                "targetProfile" : [
                  🔗 "http://hl7.eu/fhir/cancer-common/StructureDefinition/CancerConditionAtDiagnosis"
                ]
              }
            ]
          },
          {
            "id" : "SystemicTreatment.clinicalCancerProgressionReference",
            "path" : "SystemicTreatment.clinicalCancerProgressionReference",
            "short" : "ClinicalCancerProgresionReference",
            "definition" : "Reference to the clinical progression event, if treatment is delivered in response to progression.",
            "comment" : "It is not only required at the time of diagnosis; it must be provided in the event of ClinicalCancerProgression.",
            "min" : 0,
            "max" : "1",
            "base" : {
              "path" : "SystemicTreatment.clinicalCancerProgressionReference",
              "min" : 0,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "Reference",
                "targetProfile" : [
                  🔗 "http://hl7.eu/fhir/cancer-common/StructureDefinition/ClinicalCancerProgression"
                ]
              }
            ]
          },
          {
            "id" : "SystemicTreatment.intent",
            "path" : "SystemicTreatment.intent",
            "short" : "Intent",
            "definition" : "Treatment intent (Definitive/curative vs Palliative).",
            "comment" : "Choice: Definitive | Palliative",
            "min" : 1,
            "max" : "1",
            "base" : {
              "path" : "SystemicTreatment.intent",
              "min" : 1,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ]
          },
          {
            "id" : "SystemicTreatment.type",
            "path" : "SystemicTreatment.type",
            "short" : "Type",
            "definition" : "Category of systemic treatment (e.g. chemotherapy, immunotherapy, targeted therapy, hormonal therapy).",
            "min" : 1,
            "max" : "1",
            "base" : {
              "path" : "SystemicTreatment.type",
              "min" : 1,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ]
          },
          {
            "id" : "SystemicTreatment.startDate",
            "path" : "SystemicTreatment.startDate",
            "short" : "StartDate",
            "definition" : "Start date of the systemic treatment course.",
            "min" : 1,
            "max" : "1",
            "base" : {
              "path" : "SystemicTreatment.startDate",
              "min" : 1,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "dateTime"
              }
            ]
          },
          {
            "id" : "SystemicTreatment.endDate",
            "path" : "SystemicTreatment.endDate",
            "short" : "EndDate",
            "definition" : "End date of the systemic treatment course (may be missing while ongoing).",
            "comment" : "It might not be available while the treatment is still ongoing; however, an end date must eventually be recorded, which in the most extreme case will coincide with the patient's date of death.",
            "min" : 0,
            "max" : "1",
            "base" : {
              "path" : "SystemicTreatment.endDate",
              "min" : 0,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "dateTime"
              }
            ]
          },
          {
            "id" : "SystemicTreatment.ongoing",
            "path" : "SystemicTreatment.ongoing",
            "short" : "Ongoing",
            "definition" : "Indicates that the treatment is ongoing when EndDate is not available.",
            "comment" : "If the EndDate is not provided because it is ongoing, it must be indicates as True.",
            "min" : 0,
            "max" : "1",
            "base" : {
              "path" : "SystemicTreatment.ongoing",
              "min" : 0,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "boolean"
              }
            ]
          },
          {
            "id" : "SystemicTreatment.setting",
            "path" : "SystemicTreatment.setting",
            "short" : "Setting",
            "definition" : "Strategic timing/setting of systemic treatment (e.g. neoadjuvant, adjuvant, concomitant, alone).",
            "comment" : "Choice: Alone |  Preoperative/Neoadjuvant | Postoperative/Adjuvant | Concomitant",
            "min" : 0,
            "max" : "1",
            "base" : {
              "path" : "SystemicTreatment.setting",
              "min" : 0,
              "max" : "1"
            },
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ]
          }
        ]
      },
      "differential" : {
        "element" : [
          {
            "id" : "SystemicTreatment",
            "path" : "SystemicTreatment",
            "short" : "SystemicTreatment",
            "definition" : "Logical model representing a systemic anti-cancer treatment episode delivered to the patient, either at diagnosis or following disease progression. Derived from Cancer_Common_Logical_Model_20260521.xlsx (sheet SystemicTreatment).",
            "constraint" : [
              {
                "key" : "st-1",
                "severity" : "error",
                "human" : "If ongoing is true, endDate must not be present; if endDate is not present, ongoing must be true.",
                "expression" : "((ongoing = true) implies endDate.empty()) and (endDate.exists() implies (ongoing.exists().not() or ongoing = false))",
                "source" : "http://hl7.eu/fhir/cancer-common/StructureDefinition/SystemicTreatment"
              },
              {
                "key" : "st-2",
                "severity" : "warning",
                "human" : "If endDate is present, it should be greater than or equal to startDate.",
                "expression" : "endDate.empty() or endDate > startDate",
                "source" : "http://hl7.eu/fhir/cancer-common/StructureDefinition/SystemicTreatment"
              }
            ]
          },
          {
            "id" : "SystemicTreatment.subject",
            "path" : "SystemicTreatment.subject",
            "short" : "Subject",
            "definition" : "Reference to the patient (subject) receiving systemic treatment.",
            "min" : 1,
            "max" : "1",
            "type" : [
              {
                "code" : "Reference",
                "targetProfile" : [
                  🔗 "http://hl7.eu/fhir/cancer-common/StructureDefinition/CancerPatient"
                ]
              }
            ]
          },
          {
            "id" : "SystemicTreatment.cancerConditionAtDiagnosisReference",
            "path" : "SystemicTreatment.cancerConditionAtDiagnosisReference",
            "short" : "CancerConditionAtDiagnosisReference",
            "definition" : "Reference to the cancer condition at diagnosis targeted by systemic treatment.",
            "min" : 1,
            "max" : "1",
            "type" : [
              {
                "code" : "Reference",
                "targetProfile" : [
                  🔗 "http://hl7.eu/fhir/cancer-common/StructureDefinition/CancerConditionAtDiagnosis"
                ]
              }
            ]
          },
          {
            "id" : "SystemicTreatment.clinicalCancerProgressionReference",
            "path" : "SystemicTreatment.clinicalCancerProgressionReference",
            "short" : "ClinicalCancerProgresionReference",
            "definition" : "Reference to the clinical progression event, if treatment is delivered in response to progression.",
            "comment" : "It is not only required at the time of diagnosis; it must be provided in the event of ClinicalCancerProgression.",
            "min" : 0,
            "max" : "1",
            "type" : [
              {
                "code" : "Reference",
                "targetProfile" : [
                  🔗 "http://hl7.eu/fhir/cancer-common/StructureDefinition/ClinicalCancerProgression"
                ]
              }
            ]
          },
          {
            "id" : "SystemicTreatment.intent",
            "path" : "SystemicTreatment.intent",
            "short" : "Intent",
            "definition" : "Treatment intent (Definitive/curative vs Palliative).",
            "comment" : "Choice: Definitive | Palliative",
            "min" : 1,
            "max" : "1",
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ]
          },
          {
            "id" : "SystemicTreatment.type",
            "path" : "SystemicTreatment.type",
            "short" : "Type",
            "definition" : "Category of systemic treatment (e.g. chemotherapy, immunotherapy, targeted therapy, hormonal therapy).",
            "min" : 1,
            "max" : "1",
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ]
          },
          {
            "id" : "SystemicTreatment.startDate",
            "path" : "SystemicTreatment.startDate",
            "short" : "StartDate",
            "definition" : "Start date of the systemic treatment course.",
            "min" : 1,
            "max" : "1",
            "type" : [
              {
                "code" : "dateTime"
              }
            ]
          },
          {
            "id" : "SystemicTreatment.endDate",
            "path" : "SystemicTreatment.endDate",
            "short" : "EndDate",
            "definition" : "End date of the systemic treatment course (may be missing while ongoing).",
            "comment" : "It might not be available while the treatment is still ongoing; however, an end date must eventually be recorded, which in the most extreme case will coincide with the patient's date of death.",
            "min" : 0,
            "max" : "1",
            "type" : [
              {
                "code" : "dateTime"
              }
            ]
          },
          {
            "id" : "SystemicTreatment.ongoing",
            "path" : "SystemicTreatment.ongoing",
            "short" : "Ongoing",
            "definition" : "Indicates that the treatment is ongoing when EndDate is not available.",
            "comment" : "If the EndDate is not provided because it is ongoing, it must be indicates as True.",
            "min" : 0,
            "max" : "1",
            "type" : [
              {
                "code" : "boolean"
              }
            ]
          },
          {
            "id" : "SystemicTreatment.setting",
            "path" : "SystemicTreatment.setting",
            "short" : "Setting",
            "definition" : "Strategic timing/setting of systemic treatment (e.g. neoadjuvant, adjuvant, concomitant, alone).",
            "comment" : "Choice: Alone |  Preoperative/Neoadjuvant | Postoperative/Adjuvant | Concomitant",
            "min" : 0,
            "max" : "1",
            "type" : [
              {
                "code" : "CodeableConcept"
              }
            ]
          }
        ]
      }
    }