HL7 Europe Common Cancer Model
1.0.0-ballot - ballot 150

HL7 Europe Common Cancer Model - Local Development build (v1.0.0-ballot) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions

## Logical Model: CancerConditionAtDiagnosis - XML Profile

Active as of 2026-06-14

XML representation of the CancerConditionAtDiagnosis logical model.

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    <StructureDefinition xmlns="http://hl7.org/fhir">
      <id value="CancerConditionAtDiagnosis"/>
      <text>
        <status value="extensions"/>
        <div xmlns="http://www.w3.org/1999/xhtml"><p class="res-header-id"><b>Generated Narrative: StructureDefinition CancerConditionAtDiagnosis</b></p><table border="0" cellpadding="0" cellspacing="0" style="border: 0px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;"><tr style="border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top"><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="The logical name of the element">Name</a></th><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Information about the use of the element">Flags</a></th><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Minimum and Maximum # of times the element can appear in the instance">Card.</a></th><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px; width: 100px" class="hierarchy"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Reference to the type of the element">Type</a></th><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Additional information about the element">Description &amp; Constraints</a><span style="float: right"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Legend for this format"><img src="data:image/png;base64, " alt="doco" style="background-color: inherit"/></a></span></th></tr><tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_element.gif" alt="." style="background-color: white; background-color: inherit" title="Element" class="hierarchy"/> <a href="StructureDefinition-CancerConditionAtDiagnosis-definitions.html#CancerConditionAtDiagnosis" title="Logical model representing the cancer condition at first diagnosis, capturing initial tumour characteristics and the diagnostic context that initiates the cancer journey. Derived from Cancer_Common_Logical_Model_20260521.xlsx (sheet CancerConditionAtDiagnosis).">CancerConditionAtDiagnosis</a><a name="CancerConditionAtDiagnosis"> </a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a style="padding-left: 3px; padding-right: 3px; border: 1px maroon solid; font-weight: bold; color: #301212; background-color: #fdf4f4;; padding-left: 3px; padding-right: 3px; border: 1px maroon solid; font-weight: bold; color: #301212; background-color: #fdf4f4;" href="http://hl7.org/fhir/R4/conformance-rules.html#constraints" title="This element has or is affected by constraints ( ccad-1 )">C</a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="opacity: 0.5">0</span><span style="opacity: 0.5">..</span><span style="opacity: 0.5">*</span></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://build.fhir.org/types.html#Base">Base</a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">CancerConditionAtDiagnosis<br/><span style="font-weight:bold">Instances of this logical model can be the target of a Reference</span><br class="constraint"/><span title="null" class="constraint">Constraints: </span><span style="font-weight:bold" title="At least one of visitDate, biopsyDate, imagingDate, labReportDate must be present, since the model requires a diagnosis date for the Cancer Condition." class="constraint">ccad-1</span></td></tr>
    <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_reference.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Reference to another Resource" class="hierarchy"/> <a href="StructureDefinition-CancerConditionAtDiagnosis-definitions.html#CancerConditionAtDiagnosis.subject" title="Reference to the patient (subject) affected by the cancer condition at first diagnosis.">subject</a><a name="CancerConditionAtDiagnosis.subject"> </a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..1</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/references.html">Reference</a>(<a href="StructureDefinition-CancerPatient.html">Cancer Patient</a>)</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Subject</td></tr>
    <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-CancerConditionAtDiagnosis-definitions.html#CancerConditionAtDiagnosis.histologyBehaviour" title="Histology and behaviour of the neoplasm at first diagnosis. Histology describes the tumour cell type (morphology), while behaviour indicates whether the tumour is malignant, benign, carcinoma in situ, or of uncertain/borderline malignancy. This information may be unavailable during early diagnostic workup (e.g., before biopsy results are final) but is expected to be present once the diagnostic workup is completed.">histologyBehaviour</a><a name="CancerConditionAtDiagnosis.histologyBehaviour"> </a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..1</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">HistologyBehaviour</td></tr>
    <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-CancerConditionAtDiagnosis-definitions.html#CancerConditionAtDiagnosis.bodySite" title="Primary anatomical site where the cancer condition was first detected.">bodySite</a><a name="CancerConditionAtDiagnosis.bodySite"> </a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..1</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">BodySite</td></tr>
    <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-CancerConditionAtDiagnosis-definitions.html#CancerConditionAtDiagnosis.tumourGradeSystem" title="Classification system used to define tumour grade, describing how abnormal tumour cells and tissue appear under microscopic examination (e.g. Gleason for prostate cancer, FNCLCC for soft tissue sarcomas). The grading system provides an indication of the biological aggressiveness of the tumour.">tumourGradeSystem</a><a name="CancerConditionAtDiagnosis.tumourGradeSystem"> </a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..1</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">TumourGradeSystem</td></tr>
    <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-CancerConditionAtDiagnosis-definitions.html#CancerConditionAtDiagnosis.tumourGradeValue" title="Grade value assigned according to the selected TumourGradeSystem. The grade reflects the degree of cellular differentiation and biological aggressiveness of the tumour and may evolve over time.">tumourGradeValue</a><a name="CancerConditionAtDiagnosis.tumourGradeValue"> </a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..1</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#string">string</a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">TumourGradeValue</td></tr>
    <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: white; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-CancerConditionAtDiagnosis-definitions.html#CancerConditionAtDiagnosis.visitDate" title="Date of the clinical visit that established the diagnosis (one of the diagnosis dates).">visitDate</a><a name="CancerConditionAtDiagnosis.visitDate"> </a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..1</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#dateTime">dateTime</a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">VisitDate</td></tr>
    <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-CancerConditionAtDiagnosis-definitions.html#CancerConditionAtDiagnosis.biopsyDate" title="Date of the biopsy supporting the diagnosis (one of the diagnosis dates).">biopsyDate</a><a name="CancerConditionAtDiagnosis.biopsyDate"> </a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..1</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#dateTime">dateTime</a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">BiopsyDate</td></tr>
    <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: white; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-CancerConditionAtDiagnosis-definitions.html#CancerConditionAtDiagnosis.imagingDate" title="Date of the diagnostic imaging supporting the diagnosis (one of the diagnosis dates).">imagingDate</a><a name="CancerConditionAtDiagnosis.imagingDate"> </a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..1</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#dateTime">dateTime</a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">ImagingDate</td></tr>
    <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck00.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-CancerConditionAtDiagnosis-definitions.html#CancerConditionAtDiagnosis.labReportDate" title="Date of the laboratory report supporting the diagnosis, including biomarkers when applicable.">labReportDate</a><a name="CancerConditionAtDiagnosis.labReportDate"> </a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..1</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#dateTime">dateTime</a></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">LabReportDate</td></tr>
    <tr><td colspan="5" class="hierarchy"><br/><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Legend for this format"><img src="data:image/png;base64, " alt="doco" style="background-color: inherit"/> Documentation for this format</a></td></tr></table></div>
      </text>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/structuredefinition-type-characteristics">
        <valueCode value="can-be-target"/>
      </extension>
      <url
           value="http://hl7.eu/fhir/cancer-common/StructureDefinition/CancerConditionAtDiagnosis"/>
      <version value="1.0.0-ballot"/>
      <name value="CancerConditionAtDiagnosis"/>
      <title value="CancerConditionAtDiagnosis"/>
      <status value="active"/>
      <date value="2026-06-14T12:51:40+02:00"/>
      <publisher value="HL7 Europe"/>
      <contact>
        <name value="HL7 Europe"/>
        <telecom>
          <system value="url"/>
          <value value="http://hl7.eu"/>
        </telecom>
      </contact>
      <description
                   value="Logical model representing the cancer condition at first diagnosis, capturing initial tumour characteristics and the diagnostic context that initiates the cancer journey. Derived from Cancer_Common_Logical_Model_20260521.xlsx (sheet CancerConditionAtDiagnosis)."/>
      <jurisdiction>
        <coding>
          <system value="http://unstats.un.org/unsd/methods/m49/m49.htm"/>
          <code value="150"/>
          <display value="Europe"/>
        </coding>
      </jurisdiction>
      <copyright
                 value="HL7 Europe Copyright. Licensed under Common Creative License (CC0 1.0). Details at [Copyright](copyright.html)."/>
      <fhirVersion value="4.0.1"/>
      <kind value="logical"/>
      <abstract value="false"/>
      <type
            value="http://hl7.eu/fhir/cancer-common/StructureDefinition/CancerConditionAtDiagnosis"/>
      <baseDefinition value="http://hl7.org/fhir/StructureDefinition/Base"/>
      <derivation value="specialization"/>
      <snapshot>
        <extension
                   url="http://hl7.org/fhir/tools/StructureDefinition/snapshot-base-version">
          <valueString value="4.0.1"/>
        </extension>
        <element id="CancerConditionAtDiagnosis">
          <path value="CancerConditionAtDiagnosis"/>
          <short value="CancerConditionAtDiagnosis"/>
          <definition
                      value="Logical model representing the cancer condition at first diagnosis, capturing initial tumour characteristics and the diagnostic context that initiates the cancer journey. Derived from Cancer_Common_Logical_Model_20260521.xlsx (sheet CancerConditionAtDiagnosis)."/>
          <min value="0"/>
          <max value="*"/>
          <base>
            <path value="Base"/>
            <min value="0"/>
            <max value="*"/>
          </base>
          <constraint>
            <key value="ccad-1"/>
            <severity value="error"/>
            <human
                   value="At least one of visitDate, biopsyDate, imagingDate, labReportDate must be present, since the model requires a diagnosis date for the Cancer Condition."/>
            <expression
                        value="(visitDate | biopsyDate | imagingDate | labReportDate).exists()"/>
            <source
                    value="http://hl7.eu/fhir/cancer-common/StructureDefinition/CancerConditionAtDiagnosis"/>
          </constraint>
          <isModifier value="false"/>
        </element>
        <element id="CancerConditionAtDiagnosis.subject">
          <path value="CancerConditionAtDiagnosis.subject"/>
          <short value="Subject"/>
          <definition
                      value="Reference to the patient (subject) affected by the cancer condition at first diagnosis."/>
          <min value="1"/>
          <max value="1"/>
          <base>
            <path value="CancerConditionAtDiagnosis.subject"/>
            <min value="1"/>
            <max value="1"/>
          </base>
          <type>
            <code value="Reference"/>
            <targetProfile
                           value="http://hl7.eu/fhir/cancer-common/StructureDefinition/CancerPatient"/>
          </type>
        </element>
        <element id="CancerConditionAtDiagnosis.histologyBehaviour">
          <path value="CancerConditionAtDiagnosis.histologyBehaviour"/>
          <short value="HistologyBehaviour"/>
          <definition
                      value="Histology and behaviour of the neoplasm at first diagnosis. Histology describes the tumour cell type (morphology), while behaviour indicates whether the tumour is malignant, benign, carcinoma in situ, or of uncertain/borderline malignancy. This information may be unavailable during early diagnostic workup (e.g., before biopsy results are final) but is expected to be present once the diagnostic workup is completed."/>
          <comment
                   value="WG recommends ICD03, the WG will monitor possible next versions. This attribute becomes mandatory once the cancer has been diagnosed; however, during the diagnostic workup it may still be absent, as the biopsy resulting from the surgery may not yet be available."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="CancerConditionAtDiagnosis.histologyBehaviour"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="CodeableConcept"/>
          </type>
        </element>
        <element id="CancerConditionAtDiagnosis.bodySite">
          <path value="CancerConditionAtDiagnosis.bodySite"/>
          <short value="BodySite"/>
          <definition
                      value="Primary anatomical site where the cancer condition was first detected."/>
          <comment
                   value="WG recommends ICD03, the WG will monitor possible next versions. It is required to choose the most specific code available, meaning the most detailed code in the hierarchical terminology that precisely identifies the body site."/>
          <min value="1"/>
          <max value="1"/>
          <base>
            <path value="CancerConditionAtDiagnosis.bodySite"/>
            <min value="1"/>
            <max value="1"/>
          </base>
          <type>
            <code value="CodeableConcept"/>
          </type>
        </element>
        <element id="CancerConditionAtDiagnosis.tumourGradeSystem">
          <path value="CancerConditionAtDiagnosis.tumourGradeSystem"/>
          <short value="TumourGradeSystem"/>
          <definition
                      value="Classification system used to define tumour grade, describing how abnormal tumour cells and tissue appear under microscopic examination (e.g. Gleason for prostate cancer, FNCLCC for soft tissue sarcomas). The grading system provides an indication of the biological aggressiveness of the tumour."/>
          <comment
                   value="It represents the classification system used to define the tumour grade, such as Gleason (a grading system for prostate cancer) or FNCLCC (a grading system for soft tissue sarcomas)."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="CancerConditionAtDiagnosis.tumourGradeSystem"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="CodeableConcept"/>
          </type>
        </element>
        <element id="CancerConditionAtDiagnosis.tumourGradeValue">
          <path value="CancerConditionAtDiagnosis.tumourGradeValue"/>
          <short value="TumourGradeValue"/>
          <definition
                      value="Grade value assigned according to the selected TumourGradeSystem. The grade reflects the degree of cellular differentiation and biological aggressiveness of the tumour and may evolve over time."/>
          <comment
                   value="It represents the measured grade value based on the specific classification defined in the TumourGradeSystem."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="CancerConditionAtDiagnosis.tumourGradeValue"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="string"/>
          </type>
        </element>
        <element id="CancerConditionAtDiagnosis.visitDate">
          <path value="CancerConditionAtDiagnosis.visitDate"/>
          <short value="VisitDate"/>
          <definition
                      value="Date of the clinical visit that established the diagnosis (one of the diagnosis dates)."/>
          <comment
                   value="At least one of visitDate, biopsyDate, imagingDate, labReportDate must be present, since the model requires a diagnosis date for the Cancer Condition."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="CancerConditionAtDiagnosis.visitDate"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="dateTime"/>
          </type>
        </element>
        <element id="CancerConditionAtDiagnosis.biopsyDate">
          <path value="CancerConditionAtDiagnosis.biopsyDate"/>
          <short value="BiopsyDate"/>
          <definition
                      value="Date of the biopsy supporting the diagnosis (one of the diagnosis dates)."/>
          <comment
                   value="At least one of visitDate, biopsyDate, imagingDate, labReportDate must be present, since the model requires a diagnosis date for the Cancer Condition."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="CancerConditionAtDiagnosis.biopsyDate"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="dateTime"/>
          </type>
        </element>
        <element id="CancerConditionAtDiagnosis.imagingDate">
          <path value="CancerConditionAtDiagnosis.imagingDate"/>
          <short value="ImagingDate"/>
          <definition
                      value="Date of the diagnostic imaging supporting the diagnosis (one of the diagnosis dates)."/>
          <comment
                   value="At least one of visitDate, biopsyDate, imagingDate, labReportDate must be present, since the model requires a diagnosis date for the Cancer Condition."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="CancerConditionAtDiagnosis.imagingDate"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="dateTime"/>
          </type>
        </element>
        <element id="CancerConditionAtDiagnosis.labReportDate">
          <path value="CancerConditionAtDiagnosis.labReportDate"/>
          <short value="LabReportDate"/>
          <definition
                      value="Date of the laboratory report supporting the diagnosis, including biomarkers when applicable."/>
          <comment
                   value="At least one of visitDate, biopsyDate, imagingDate, labReportDate must be present, since the model requires a diagnosis date for the Cancer Condition."/>
          <min value="0"/>
          <max value="1"/>
          <base>
            <path value="CancerConditionAtDiagnosis.labReportDate"/>
            <min value="0"/>
            <max value="1"/>
          </base>
          <type>
            <code value="dateTime"/>
          </type>
        </element>
      </snapshot>
      <differential>
        <element id="CancerConditionAtDiagnosis">
          <path value="CancerConditionAtDiagnosis"/>
          <short value="CancerConditionAtDiagnosis"/>
          <definition
                      value="Logical model representing the cancer condition at first diagnosis, capturing initial tumour characteristics and the diagnostic context that initiates the cancer journey. Derived from Cancer_Common_Logical_Model_20260521.xlsx (sheet CancerConditionAtDiagnosis)."/>
          <constraint>
            <key value="ccad-1"/>
            <severity value="error"/>
            <human
                   value="At least one of visitDate, biopsyDate, imagingDate, labReportDate must be present, since the model requires a diagnosis date for the Cancer Condition."/>
            <expression
                        value="(visitDate | biopsyDate | imagingDate | labReportDate).exists()"/>
            <source
                    value="http://hl7.eu/fhir/cancer-common/StructureDefinition/CancerConditionAtDiagnosis"/>
          </constraint>
        </element>
        <element id="CancerConditionAtDiagnosis.subject">
          <path value="CancerConditionAtDiagnosis.subject"/>
          <short value="Subject"/>
          <definition
                      value="Reference to the patient (subject) affected by the cancer condition at first diagnosis."/>
          <min value="1"/>
          <max value="1"/>
          <type>
            <code value="Reference"/>
            <targetProfile
                           value="http://hl7.eu/fhir/cancer-common/StructureDefinition/CancerPatient"/>
          </type>
        </element>
        <element id="CancerConditionAtDiagnosis.histologyBehaviour">
          <path value="CancerConditionAtDiagnosis.histologyBehaviour"/>
          <short value="HistologyBehaviour"/>
          <definition
                      value="Histology and behaviour of the neoplasm at first diagnosis. Histology describes the tumour cell type (morphology), while behaviour indicates whether the tumour is malignant, benign, carcinoma in situ, or of uncertain/borderline malignancy. This information may be unavailable during early diagnostic workup (e.g., before biopsy results are final) but is expected to be present once the diagnostic workup is completed."/>
          <comment
                   value="WG recommends ICD03, the WG will monitor possible next versions. This attribute becomes mandatory once the cancer has been diagnosed; however, during the diagnostic workup it may still be absent, as the biopsy resulting from the surgery may not yet be available."/>
          <min value="0"/>
          <max value="1"/>
          <type>
            <code value="CodeableConcept"/>
          </type>
        </element>
        <element id="CancerConditionAtDiagnosis.bodySite">
          <path value="CancerConditionAtDiagnosis.bodySite"/>
          <short value="BodySite"/>
          <definition
                      value="Primary anatomical site where the cancer condition was first detected."/>
          <comment
                   value="WG recommends ICD03, the WG will monitor possible next versions. It is required to choose the most specific code available, meaning the most detailed code in the hierarchical terminology that precisely identifies the body site."/>
          <min value="1"/>
          <max value="1"/>
          <type>
            <code value="CodeableConcept"/>
          </type>
        </element>
        <element id="CancerConditionAtDiagnosis.tumourGradeSystem">
          <path value="CancerConditionAtDiagnosis.tumourGradeSystem"/>
          <short value="TumourGradeSystem"/>
          <definition
                      value="Classification system used to define tumour grade, describing how abnormal tumour cells and tissue appear under microscopic examination (e.g. Gleason for prostate cancer, FNCLCC for soft tissue sarcomas). The grading system provides an indication of the biological aggressiveness of the tumour."/>
          <comment
                   value="It represents the classification system used to define the tumour grade, such as Gleason (a grading system for prostate cancer) or FNCLCC (a grading system for soft tissue sarcomas)."/>
          <min value="0"/>
          <max value="1"/>
          <type>
            <code value="CodeableConcept"/>
          </type>
        </element>
        <element id="CancerConditionAtDiagnosis.tumourGradeValue">
          <path value="CancerConditionAtDiagnosis.tumourGradeValue"/>
          <short value="TumourGradeValue"/>
          <definition
                      value="Grade value assigned according to the selected TumourGradeSystem. The grade reflects the degree of cellular differentiation and biological aggressiveness of the tumour and may evolve over time."/>
          <comment
                   value="It represents the measured grade value based on the specific classification defined in the TumourGradeSystem."/>
          <min value="0"/>
          <max value="1"/>
          <type>
            <code value="string"/>
          </type>
        </element>
        <element id="CancerConditionAtDiagnosis.visitDate">
          <path value="CancerConditionAtDiagnosis.visitDate"/>
          <short value="VisitDate"/>
          <definition
                      value="Date of the clinical visit that established the diagnosis (one of the diagnosis dates)."/>
          <comment
                   value="At least one of visitDate, biopsyDate, imagingDate, labReportDate must be present, since the model requires a diagnosis date for the Cancer Condition."/>
          <min value="0"/>
          <max value="1"/>
          <type>
            <code value="dateTime"/>
          </type>
        </element>
        <element id="CancerConditionAtDiagnosis.biopsyDate">
          <path value="CancerConditionAtDiagnosis.biopsyDate"/>
          <short value="BiopsyDate"/>
          <definition
                      value="Date of the biopsy supporting the diagnosis (one of the diagnosis dates)."/>
          <comment
                   value="At least one of visitDate, biopsyDate, imagingDate, labReportDate must be present, since the model requires a diagnosis date for the Cancer Condition."/>
          <min value="0"/>
          <max value="1"/>
          <type>
            <code value="dateTime"/>
          </type>
        </element>
        <element id="CancerConditionAtDiagnosis.imagingDate">
          <path value="CancerConditionAtDiagnosis.imagingDate"/>
          <short value="ImagingDate"/>
          <definition
                      value="Date of the diagnostic imaging supporting the diagnosis (one of the diagnosis dates)."/>
          <comment
                   value="At least one of visitDate, biopsyDate, imagingDate, labReportDate must be present, since the model requires a diagnosis date for the Cancer Condition."/>
          <min value="0"/>
          <max value="1"/>
          <type>
            <code value="dateTime"/>
          </type>
        </element>
        <element id="CancerConditionAtDiagnosis.labReportDate">
          <path value="CancerConditionAtDiagnosis.labReportDate"/>
          <short value="LabReportDate"/>
          <definition
                      value="Date of the laboratory report supporting the diagnosis, including biomarkers when applicable."/>
          <comment
                   value="At least one of visitDate, biopsyDate, imagingDate, labReportDate must be present, since the model requires a diagnosis date for the Cancer Condition."/>
          <min value="0"/>
          <max value="1"/>
          <type>
            <code value="dateTime"/>
          </type>
        </element>
      </differential>
    </StructureDefinition>