## ValueSet Comparison between http://hl7.eu/fhir/laboratory/ValueSet/lab-certifiedRefMaterial-eu-lab vs http://hl7.eu/fhir/laboratory/ValueSet/lab-certifiedRefMaterial-eu-lab

### Messages

Error | ValueSet.version | Values for version differ: '0.1.1' vs '2.0.0-alpha'
Information | ValueSet.date | Values for date differ: '2025-03-25T12:00:10+01:00' vs '2026-02-25T15:28:07+01:00'

### Metadata

Name | Value | Comments
--- | --- | ---
compose.inactive |  |
compose.lockedDate |  |
copyright | This material contains content from the NIBSC Product list (https://nibsc.org/NIBSC%20Product%20List%20-%20Feb%2024.pdf). The National Institute for Biological Standards and Control part of the UK Medicines and Healthcare products Regulatory Agency (MHRA). |
date | 2025-03-25T12:00:10+01:00 | 2026-02-25T15:28:07+01:00 | Values Differ
description | List of the coded concepts describing the certified reference material used for the calibration, typically used when the unit of the result is UCUM [IU]. |
experimental | true |
immutable |  |
jurisdiction |  |
jurisdiction[0] | http://unstats.un.org/unsd/methods/m49/m49.htm#150 |
name | LabCertifiedReferenceMaterialVS |
publisher | HL7 Europe |
purpose |  |
status | draft |
title | Laboratory Certified Reference Material |
url | http://hl7.eu/fhir/laboratory/ValueSet/lab-certifiedRefMaterial-eu-lab |
version | 0.1.1 | 2.0.0-alpha | Values Differ

### Definition

Item | Property | Value | Comments
--- | --- | --- | ---
include | http://nibsc.org |  |
Concept | 06/140 | Pertussis antiserum (human), anti-PT IgG, Lyophilized, 335 IU and anti-PT IgA 65 IU / ampoule; anti-FHA IgG 130 IU and anti-FHA IgA 65 IU / ampoule; anti-69K IgG 65 IU and anti-PT IgA 42 IU / ampoule |
Concept | 00/588 | Hepatitis B virus surface antigen, subtype adw2, genotype A, Lyophilized, 33 IU/vial. |
Concept | 01/600 | Anti-toxoplasma serum (IgG), Lyophilized, 20 IU / ampoule. |
Concept | 01/608 | Low Molecular Weight Heparin |
Concept | 02/150 | Blood Coagulation Factor VIII and Von Willebrand Factor in Plasma, Human |
Concept | 02/206 | Blood coagulation factor XIII, Lyophilized, Activity 0.91 IU/ampoule; Antigen 0.93 IU/ampoule |
Concept | 02/342 | Protein C, Lyophilized, 0.85 IU/ampoule (function), 0.84 IU/ampoule (antigen). |
Concept | 03/116 | Blood coagulation factor V, Lyophilized, 0.74 IU of Factor V:C per ampoule |
Concept | 03/228 | Protein S, Lyophilized, 0.83 IU/ampoule (total antigen), 0.81 IU/ampoule (free antigen), 0.77 IU/ampoule (function). |
Concept | 04/102 | Blood coagulation factor XI, plasma human, Lyophilized., 0.86 International Units per ampoule |
Concept | 07/164 | Anti-hepatitis B immunoglobulin, Lyophilized, 100 IU/ampoule |
Concept | 07/316 | Blood coagulation factor VIII and von Willebrand factor, Lyophilized, Factor VIII: C 0.68 IU/ amp; Factor VIII:Antigen 1.04 IU/ amp; VWF:Antigen 1.00 IU/ amp; VWF:Ristocetin cofactor 0.87 IU/amp; VWF:Collagen binding 1.03 IU/amp; VWFpp 1.03 IU/amp |
Concept | 07/364 | Chorionic gonadotrophin, Lyophilized 179 International Units or 0.39 nmol per ampoule for calibration of immunossays, and 162 International Units per ampoule for calibration of biossay, , |
Concept | 08/204 | Thyroid-stimulating antibody, Lyophilized, 0.113 IU / ampoule. |
Concept | 08/258 | Antithrombin, Lyophilized, Functional potency - 0.95 IU/ampoule, Antigenic potency - 0.96 IU/ampoule |
Concept | 08/266 | Sex hormone binding globulin (SHBG), Lyophilized, 180 IU / ampoule. |
Concept | 09/162 | Human cytomegalovirus DNA, Lyophilized, 5,000,000 IU/vial. |
Concept | 09/172 | Blood coagulation factors II, VII, IX, X, Lyophilized, 0.89 IU (factor II), 0.99 IU (factor VII), 0.9 IU (factor IX), 0.89 IU (factor X) / ampoule. |
Concept | 09/260 | Epstein Barr virus DNA, Lyophilized, 5,000,000 IU/ml |
Concept | 09/264 | Fibrinogen, Lyophilized, 2.7 mg/ampoule |
Concept | 10/152 | HIV-1 RNA, Lyophilized, 185,000 IU/ml (5.27 log10 IU/ml) |
Concept | 10/262 | Diphtheria Antitoxin Human IgG, Lyophilized, 2 IU / ampoule |
Concept | 10/264 | Hepatitis B virus DNA, Lyophilized., 850,000 IU / vial. |
Concept | 11/176 | Heparin, low molecular weight, Lyophilized, Anti-Xa: 1068 IU/ampoule, Anti-Iia: 342 IU/ampoule |
Concept | 11/234 | Human serum immunoglobulin E, Lyophilized, 13,500 IU/mL |
Concept | 11/700 | Erythropoietin, rDNA-derived, Lyophilized, 1,650 IU / ampoule. |
Concept | 12/252 | A Disintegrin And Metalloprotease with ThromboSpondin type 1 motifs 13 (ADAMTS13), plasma, Lyophilized., Function: 0.91 IU/ampoule Antigen: 0.92 IU/ampoule |
Concept | 14/114 | JC polyomavirus DNA, Lyophilized., 7.0 log10 IU/ mL |
Concept | 14/212 | BK polyomavirus DNA, Lyophilized., 7.2 log10 IU/ mL |
Concept | 15/180 | Factor XI, plasma, human, Lyophilized, Functional activity: 0.71 IU per ampoule, Antigen: 0.78 IU per ampoule |
Concept | 16/368 | HSV-1 |
Concept | 17/100 | Prostate Specific Antigen (human)(total: PSA-ACT + free PSA) |
Concept | 17/122 | HSV-2 |
Concept | 66/304 | Insulin, human, for immunoassay, Lyophilized, 3 IU / ampoule. |
Concept | 67/086 | Human serum immunoglobulins G, A, and M (IgG, IgA and IgM), Lyophilized, 100 IU IgG, 100 IU IgA and 100 IU IgM/ampoule. |
Concept | 67/343 | Erythropoietin, human, urinary, Lyophilized, 10 IU / ampoule. |
Concept | 68/356 | Renin, human, Lyophilized, 0.1 IU / ampoule. |
Concept | 69/194 | Glucagon, porcine, Lyophilized, 1.49 IU / ampoule. |
Concept | 73/545 | Placental lactogen, human, for immunoassay, Lyophilized, 0.000 850 IU / ampoule. |
Concept | 73/601 | Carcinoembryonic antigen (CEA), Lyophilized, 100 IU/ampoule |
Concept | 75/551 | Chorionic gonadotrophin, beta subunit, human, for immunoassay, Lyophilized, 70 IU / ampoule. |
Concept | 75/569 | Chorionic gonadotrophin, alpha subunit, human, for immunoassay, Lyophilized, 70 IU / ampoule. |
Concept | 75/589 | Chorionic gonadotrophin, human, Lyophilized, 650 IU / ampoule. |
Concept | 78/554 | Luteinizing hormone, human, pituitary, alpha subunit, Lyophilized, 10 IU / ampoule. |
Concept | 78/556 | Luteinizing hormone, human, pituitary, beta subunit, Lyophilized, 10 IU / ampoule. |
Concept | 79/500 | Parathyroid hormone, human, for immunoassay, Lyophilized, 0.1 IU / ampoule. |
Concept | 80/505 | Human growth hormone, pituitary, Lyophilized, 4.4 IU / ampoule. |
Concept | 80/552 | Luteinizing hormone, human, pituitary, Lyophilized, 35 IU / ampoule. |
Concept | 81/565 | Thyroid stimulating hormone, human, for immunoassay, Lyophilized, 11.5 x -3 log 10 IU / ampoule. |
Concept | 82/585 | Anti-poliovirus serum (Types 1, 2, 3), Lyophilized, 11 IU/ampoule (Type 1), 32 IU/ampoule (Type 2), 3 IU/ampoule (Type 3) |
Concept | 82/587 | Interferon Gamma (Human, Leukocyte derived) |
Concept | 83/501 | Beta-thromboglobulin, Lyophilized, 500 IU/ampoule. |
Concept | 83/505 | Platelet factor 4, Lyophilized, 400 IU/ampoule |
Concept | 83/575 | Follicle stimulating hormone, human, pituitary, Lyophilized, 80 IU / ampoule. |
Concept | 84/500 | Prolactin, human, Lyophilized., 0.053 IU / ampoule. |
Concept | 85/506 | C-reactive protein, Lyophilized, 0.049 IU/ampoule |
Concept | 85/669 | Atrial natriuretic factor, human, Lyophilized, 2.5 IU / ampoule. |
Concept | 88/638 | Thyroxine-binding globulin, Lyophilized, 30 IU / ampoule. |
Concept | 89/620 | Calcitonin, human, Lyophilized, 17.5 IU / ampoule. |
Concept | 91/554 | Insulin-like growth factor I for bioassay, Lyophilized, 150 IU / ampoule. |
Concept | 91/624 | Inhibin A, human, recombinant, Lyophilized, 150,000 IU / ampoule. |
Concept | 92/510 | Follicle stimulating hormone, human, recombinant for immunoassay, Lyophilized, 60 IU / ampoule. |
Concept | 92/654 | Plasminogen-Activator Inhibitor 1 (PAI-1), Lyophilized, Tissueplasminogen-activator: 27.5 IU of neutralising activity/ampoule. Urinary-plasminogen-activator: 7 IU of neutralising activity/ampoule. |
Concept | 94/572 | Ferritin, recombinant, Lyophilized, 6.3 μg/ampoule |
Concept | 96/670 | Prostate specific antigen (90:10), Lyophilized, 1 μg total PSA per vial. |
Concept | 97/550 | Islet cell antibodies, Lyophilized, 20 units/ampoule of islet cell antibodies; 100 units/ampoule of anti-GAD65; 100 units/ampoule of anti-IA-2. |
Concept | 97/646 | Anti-Hepatitis A Immunoglobulin, Human (W1041) WHO International Standard |
Concept | 98/574 | Somatropin (rDNA-derived human growth hormone), Lyophilized, 1.95 mg protein / ampoule. |
Concept | AFP | Alphafoetoprotein, Lyophilized, 100,000 IU / ampoule. |
Concept | RAI | Anti-rabies immunoglobulin, Lyophilized, 30 IU/ampoule |
Concept | rTF/16 | Thromboplastin, Human, Recombinant, Plain 5th International Standard 2016. |
Concept | RUBI-1-94 | Anti-rubella immunoglobulin, Lyophilized, 1,600 IU/vial |
Concept | W1066 | Rheumatoid arthritis serum, Lyophilized, 100 IU/ampoule |
include | http://pei.de |  |
Concept | 7657/12 | Hepatitis D virus RNA, Lyophilized, 575,000 IU/mL |
include | http://niaid.nih.gov |  |
Concept | Gxg01-902535 | Interferon gamma, human, recombinant, Lyophilized, 80,000 IU / ampoule. |

### Expansion

Unable to generate expansion - see errors