IDEA4RC FHIR Implementation Guide
1.0.0 - release 150

This page is part of the IDEA4RC FHIR Implementation Guide (v1.0.0: QA Preview) based on FHIR (HL7® FHIR® Standard) R4. This is the current published version. For a full list of available versions, see the Directory of published versions

: Cancer histology subgroup: Athena - XML Representation

Active as of 2026-09-17

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<ValueSet xmlns="http://hl7.org/fhir">
  <id value="cancer-histology-subgroup-athena-vs"/>
  <text>
    <status value="extensions"/>
    <div xmlns="http://www.w3.org/1999/xhtml"><p class="res-header-id"><b>Generated Narrative: ValueSet cancer-histology-subgroup-athena-vs</b></p><a name="cancer-histology-subgroup-athena-vs"> </a><a name="hccancer-histology-subgroup-athena-vs"> </a><p>This value set includes codes based on the following rules:</p><ul><li>Include these codes as defined in <code>http://fhir.ohdsi.org/CodeSystem/concepts</code><span title="Version is not explicitly stated. No matching Code System found"> version Not Stated (use latest from terminology server)</span><table class="none"><tr><td style="white-space:nowrap"><b>Code</b></td><td><b>Display</b></td></tr><tr><td>4078953</td><td>Squamous cell carcinoma, keratinizing</td></tr><tr><td>4166826</td><td>Squamous cell carcinoma, large cell, nonkeratinizing</td></tr><tr><td>4206785</td><td>Schneiderian carcinoma</td></tr><tr><td>4009590</td><td>Squamous cell carcinoma, spindle cell</td></tr><tr><td>4247661</td><td>Lymphoepithelial carcinoma</td></tr><tr><td>4029973</td><td>Basaloid squamous cell carcinoma</td></tr><tr><td>37156145</td><td>Squamous cell carcinoma</td></tr><tr><td>4312219</td><td>Adenoid squamous cell carcinoma</td></tr><tr><td>4052146</td><td>Squamous cell carcinoma, microinvasive</td></tr><tr><td>4175678</td><td>Giant cell carcinoma</td></tr><tr><td>4233949</td><td>Verrucous carcinoma</td></tr><tr><td>4191609</td><td>Papillary squamous cell carcinoma</td></tr><tr><td>37204531</td><td>Human papillomavirus positive squamous cell carcinoma</td></tr><tr><td>37204532</td><td>Human papillomavirus negative squamous cell carcinoma</td></tr><tr><td>4097305</td><td>Adenocarcinoma, intestinal type</td></tr><tr><td>37152526</td><td>Adenocarcinoma</td></tr><tr><td>4050978</td><td>Cystoadenocarcinoma</td></tr><tr><td>4247921</td><td>Mucinous adenocarcinoma</td></tr><tr><td>4238334</td><td>Ceruminous adenocarcinoma</td></tr><tr><td>4172953</td><td>Papillary adenocarcinoma</td></tr><tr><td>4022895</td><td>Adenoid cystic carcinoma</td></tr><tr><td>4253608</td><td>Mucoepidermoid carcinoma</td></tr><tr><td>4030121</td><td>Polymorphous low grade adenocarcinoma</td></tr><tr><td>4164740</td><td>Acinar cell carcinoma</td></tr><tr><td>4148292</td><td>Clear cell adenocarcinoma</td></tr><tr><td>4146684</td><td>Basal cell adenocarcinoma</td></tr><tr><td>4221403</td><td>Infiltrating duct carcinoma</td></tr><tr><td>4224593</td><td>Juvenile carcinoma of the breast</td></tr><tr><td>4323699</td><td>Paget's disease, extramammary (except Paget's disease of bone)</td></tr><tr><td>4321002</td><td>Epithelial-myoepithelial carcinoma</td></tr><tr><td>4066512</td><td>Carcinoma ex pleomorphic adenoma</td></tr><tr><td>4182993</td><td>Sebaceous adenocarcinoma</td></tr><tr><td>4271564</td><td>Carcinosarcoma</td></tr><tr><td>4212379</td><td>Oxyphilic adenocarcinoma</td></tr><tr><td>36714029</td><td>Small cell neuroendocrine carcinoma (SmCC)</td></tr><tr><td>37018672</td><td>Malignant poorly differentiated neuroendocrine carcinoma</td></tr><tr><td>4029971</td><td>Large cell neuroendocrine carcinoma (LCNEC)</td></tr><tr><td>4133828</td><td>Neuroendocrine tumor grade 1</td></tr><tr><td>4133297</td><td>Neuroendocrine tumor grade 2</td></tr><tr><td>1242310</td><td>Neuroendocrine carcinoma</td></tr><tr><td>4098585</td><td>Odontogenic tumor, malignant</td></tr><tr><td>37116966</td><td>Clear cell odontogenic carcinoma</td></tr><tr><td>4005818</td><td>Malignant odontogenic ghost cell tumor</td></tr><tr><td>44783808</td><td>Undifferentiated carcinoma of nasal sinus</td></tr><tr><td>4243327</td><td>Carcinoma, undifferentiated</td></tr><tr><td>4241843</td><td>Adenosquamous carcinoma</td></tr><tr><td>4284401</td><td>Teratocarcinoma</td></tr><tr><td>37116896</td><td>Nuclear protein in testis associated carcinoma</td></tr><tr><td>4295574</td><td>Olfactory neuroblastoma</td></tr><tr><td>4021372</td><td>Atypical lipomatous tumor</td></tr><tr><td>4102790</td><td>Liposarcoma, well differentiated</td></tr><tr><td>4284833</td><td>Dedifferentiated liposarcoma</td></tr><tr><td>4101123</td><td>Myxoid liposarcoma</td></tr><tr><td>4010104</td><td>Pleomorphic liposarcoma</td></tr><tr><td>1243142</td><td>Myxoid pleomorphic liposarcoma</td></tr><tr><td>4264204</td><td>Aggressive fibromatosis</td></tr><tr><td>4295283</td><td>Dermatofibrosarcoma protuberans</td></tr><tr><td>4207381</td><td>Epithelioid haemangioendothelioma</td></tr><tr><td>3661612</td><td>Angiosarcoma</td></tr><tr><td>4029021</td><td>Undifferentiated sarcoma</td></tr><tr><td>4239519</td><td>Myoepithelioma</td></tr><tr><td>4029680</td><td>Myoepithelial carcinoma</td></tr><tr><td>4028565</td><td>Ossifying fibromyxoid tumour</td></tr><tr><td>4195947</td><td>Mesenchymoma</td></tr><tr><td>45766484</td><td>Phosphaturic mesenchymal tumor, benign</td></tr><tr><td>45766485</td><td>Phosphaturic mesenchymal tumour, malignant</td></tr><tr><td>4239956</td><td>Angiomyxoma</td></tr><tr><td>4029526</td><td>Angiomatoid fibrous histiocytoma</td></tr><tr><td>45766528</td><td>Ewing sarcoma / peripheral neuroectodermal tumor</td></tr><tr><td>37311513</td><td>Biphenotypic sinonasal sarcoma</td></tr><tr><td>4135215</td><td>Adenosarcoma</td></tr></table></li><li>Include these codes as defined in <a href="CodeSystem-cs-idea4rc-vocab-eu-i4rc.html"><code>http://hl7.eu/fhir/ig/idea4rc/CodeSystem/cs-idea4rc-vocab-eu-i4rc</code></a><span title="Version is not explicitly stated, which means it is fixed to the version provided in this specification"> version &#x1F4E6;1.0.0</span><table class="none"><tr><td style="white-space:nowrap"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td><a href="CodeSystem-cs-idea4rc-vocab-eu-i4rc.html#cs-idea4rc-vocab-eu-i4rc-2000100012">2000100012</a></td><td>Non-keratinizing squamous cell carcinoma: SMARCB1 (INI-1)-deficient Sinonasal Carcinoma</td><td>Non-keratinizing squamous cell carcinoma: SMARCB1 (INI-1)-deficient Sinonasal Carcinoma</td></tr><tr><td><a href="CodeSystem-cs-idea4rc-vocab-eu-i4rc.html#cs-idea4rc-vocab-eu-i4rc-2000100013">2000100013</a></td><td>Non-keratinizing squamous cell carcinoma: Transitional (cylindrical cell, Schneiderian) carcinoma</td><td>Non-keratinizing squamous cell carcinoma: Transitional (cylindrical cell, Schneiderian) carcinoma</td></tr><tr><td><a href="CodeSystem-cs-idea4rc-vocab-eu-i4rc.html#cs-idea4rc-vocab-eu-i4rc-2000100014">2000100014</a></td><td>Spindle cell (sarcomatoid) squamous cell carcinoma: SMARCB1 (INI-1)</td><td>Spindle cell (sarcomatoid) squamous cell carcinoma: SMARCB1 (INI-1)</td></tr><tr><td><a href="CodeSystem-cs-idea4rc-vocab-eu-i4rc.html#cs-idea4rc-vocab-eu-i4rc-2000100015">2000100015</a></td><td>SMARCB1 (INI-1)-deficient Sinonasal undifferentiated Carcinoma</td><td>SMARCB1 (INI-1)-deficient Sinonasal undifferentiated Carcinoma</td></tr><tr><td><a href="CodeSystem-cs-idea4rc-vocab-eu-i4rc.html#cs-idea4rc-vocab-eu-i4rc-2000100016">2000100016</a></td><td>Sinonasal SMARCA4 deficient carcinoma</td><td>Sinonasal SMARCA4 deficient carcinoma</td></tr><tr><td><a href="CodeSystem-cs-idea4rc-vocab-eu-i4rc.html#cs-idea4rc-vocab-eu-i4rc-2000100017">2000100017</a></td><td>IDH2-mutated sinonasal undifferentiated neoplasm</td><td>IDH2-mutated sinonasal undifferentiated neoplasm</td></tr><tr><td><a href="CodeSystem-cs-idea4rc-vocab-eu-i4rc.html#cs-idea4rc-vocab-eu-i4rc-2000100018">2000100018</a></td><td>HPV-related Multiphenotypic Sinonasal Carcinoma</td><td>HPV-related Multiphenotypic Sinonasal Carcinoma</td></tr><tr><td><a href="CodeSystem-cs-idea4rc-vocab-eu-i4rc.html#cs-idea4rc-vocab-eu-i4rc-2000100019">2000100019</a></td><td>NTRK-rearranged spindle cell neoplasm (emerging)</td><td>NTRK-rearranged spindle cell neoplasm (emerging)</td></tr></table></li></ul></div>
  </text>
  <url
       value="http://hl7.eu/fhir/ig/idea4rc/ValueSet/cancer-histology-subgroup-athena-vs"/>
  <version value="1.0.0"/>
  <name value="CancerHistologySubgroupVS"/>
  <title value="Cancer histology subgroup: Athena"/>
  <status value="active"/>
  <experimental value="false"/>
  <date value="2026-09-17T14:38:18+02:00"/>
  <publisher value="IDEA4RC Project"/>
  <contact>
    <name value="IDEA4RC Project"/>
    <telecom>
      <system value="url"/>
      <value value="https://www.idea4rc.eu/"/>
    </telecom>
  </contact>
  <contact>
    <name value="IDEA4RC Project"/>
    <telecom>
      <system value="url"/>
      <value value="https://www.idea4rc.eu/"/>
    </telecom>
  </contact>
  <description
               value="Codes identifing the histology subgroup of the cancer."/>
  <jurisdiction>
    <coding>
      <system value="http://unstats.un.org/unsd/methods/m49/m49.htm"/>
      <code value="150"/>
      <display value="Europe"/>
    </coding>
  </jurisdiction>
  <copyright
             value="Copyright 2018 Odysseus Data Services, inc.
Licensed under the Apache License, Version 2.0 (the &quot;License&quot;) you may not use this file except in compliance with the License.
You may obtain a copy of the License at  http://www.apache.org/licenses/LICENSE-2.0
Unless required by applicable law or agreed to in writing, software distributed under the License is distributed on an 'AS IS' BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
See the License for the specific language governing permissions and limitations under the License.   Company: Odysseus Data Services, Inc. Product Owner/Architecture: Gregory Klebanov Authors: Anastasiia Klochkova"/>
  <compose>
    <include>
      <system value="http://fhir.ohdsi.org/CodeSystem/concepts"/>
      <concept>
        <code value="4078953"/>
        <display value="Squamous cell carcinoma, keratinizing"/>
      </concept>
      <concept>
        <code value="4166826"/>
        <display
                 value="Squamous cell carcinoma, large cell, nonkeratinizing"/>
      </concept>
      <concept>
        <code value="4206785"/>
        <display value="Schneiderian carcinoma"/>
      </concept>
      <concept>
        <code value="4009590"/>
        <display value="Squamous cell carcinoma, spindle cell"/>
      </concept>
      <concept>
        <code value="4247661"/>
        <display value="Lymphoepithelial carcinoma"/>
      </concept>
      <concept>
        <code value="4029973"/>
        <display value="Basaloid squamous cell carcinoma"/>
      </concept>
      <concept>
        <code value="37156145"/>
        <display value="Squamous cell carcinoma"/>
      </concept>
      <concept>
        <code value="4312219"/>
        <display value="Adenoid squamous cell carcinoma"/>
      </concept>
      <concept>
        <code value="4052146"/>
        <display value="Squamous cell carcinoma, microinvasive"/>
      </concept>
      <concept>
        <code value="4175678"/>
        <display value="Giant cell carcinoma"/>
      </concept>
      <concept>
        <code value="4233949"/>
        <display value="Verrucous carcinoma"/>
      </concept>
      <concept>
        <code value="4191609"/>
        <display value="Papillary squamous cell carcinoma"/>
      </concept>
      <concept>
        <code value="37204531"/>
        <display
                 value="Human papillomavirus positive squamous cell carcinoma"/>
      </concept>
      <concept>
        <code value="37204532"/>
        <display
                 value="Human papillomavirus negative squamous cell carcinoma"/>
      </concept>
      <concept>
        <code value="4097305"/>
        <display value="Adenocarcinoma, intestinal type"/>
      </concept>
      <concept>
        <code value="37152526"/>
        <display value="Adenocarcinoma"/>
      </concept>
      <concept>
        <code value="4050978"/>
        <display value="Cystoadenocarcinoma"/>
      </concept>
      <concept>
        <code value="4247921"/>
        <display value="Mucinous adenocarcinoma"/>
      </concept>
      <concept>
        <code value="4238334"/>
        <display value="Ceruminous adenocarcinoma"/>
      </concept>
      <concept>
        <code value="4172953"/>
        <display value="Papillary adenocarcinoma"/>
      </concept>
      <concept>
        <code value="4022895"/>
        <display value="Adenoid cystic carcinoma"/>
      </concept>
      <concept>
        <code value="4253608"/>
        <display value="Mucoepidermoid carcinoma"/>
      </concept>
      <concept>
        <code value="4030121"/>
        <display value="Polymorphous low grade adenocarcinoma"/>
      </concept>
      <concept>
        <code value="4164740"/>
        <display value="Acinar cell carcinoma"/>
      </concept>
      <concept>
        <code value="4148292"/>
        <display value="Clear cell adenocarcinoma"/>
      </concept>
      <concept>
        <code value="4146684"/>
        <display value="Basal cell adenocarcinoma"/>
      </concept>
      <concept>
        <code value="4221403"/>
        <display value="Infiltrating duct carcinoma"/>
      </concept>
      <concept>
        <code value="4224593"/>
        <display value="Juvenile carcinoma of the breast"/>
      </concept>
      <concept>
        <code value="4323699"/>
        <display
                 value="Paget's disease, extramammary (except Paget's disease of bone)"/>
      </concept>
      <concept>
        <code value="4321002"/>
        <display value="Epithelial-myoepithelial carcinoma"/>
      </concept>
      <concept>
        <code value="4066512"/>
        <display value="Carcinoma ex pleomorphic adenoma"/>
      </concept>
      <concept>
        <code value="4182993"/>
        <display value="Sebaceous adenocarcinoma"/>
      </concept>
      <concept>
        <code value="4271564"/>
        <display value="Carcinosarcoma"/>
      </concept>
      <concept>
        <code value="4212379"/>
        <display value="Oxyphilic adenocarcinoma"/>
      </concept>
      <concept>
        <code value="36714029"/>
        <display value="Small cell neuroendocrine carcinoma (SmCC)"/>
      </concept>
      <concept>
        <code value="37018672"/>
        <display
                 value="Malignant poorly differentiated neuroendocrine carcinoma"/>
      </concept>
      <concept>
        <code value="4029971"/>
        <display value="Large cell neuroendocrine carcinoma (LCNEC)"/>
      </concept>
      <concept>
        <code value="4133828"/>
        <display value="Neuroendocrine tumor grade 1"/>
      </concept>
      <concept>
        <code value="4133297"/>
        <display value="Neuroendocrine tumor grade 2"/>
      </concept>
      <concept>
        <code value="1242310"/>
        <display value="Neuroendocrine carcinoma"/>
      </concept>
      <concept>
        <code value="4098585"/>
        <display value="Odontogenic tumor, malignant"/>
      </concept>
      <concept>
        <code value="37116966"/>
        <display value="Clear cell odontogenic carcinoma"/>
      </concept>
      <concept>
        <code value="4005818"/>
        <display value="Malignant odontogenic ghost cell tumor"/>
      </concept>
      <concept>
        <code value="44783808"/>
        <display value="Undifferentiated carcinoma of nasal sinus"/>
      </concept>
      <concept>
        <code value="4243327"/>
        <display value="Carcinoma, undifferentiated"/>
      </concept>
      <concept>
        <code value="4241843"/>
        <display value="Adenosquamous carcinoma"/>
      </concept>
      <concept>
        <code value="4284401"/>
        <display value="Teratocarcinoma"/>
      </concept>
      <concept>
        <code value="37116896"/>
        <display value="Nuclear protein in testis associated carcinoma"/>
      </concept>
      <concept>
        <code value="4295574"/>
        <display value="Olfactory neuroblastoma"/>
      </concept>
      <concept>
        <code value="4021372"/>
        <display value="Atypical lipomatous tumor"/>
      </concept>
      <concept>
        <code value="4102790"/>
        <display value="Liposarcoma, well differentiated"/>
      </concept>
      <concept>
        <code value="4284833"/>
        <display value="Dedifferentiated liposarcoma"/>
      </concept>
      <concept>
        <code value="4101123"/>
        <display value="Myxoid liposarcoma"/>
      </concept>
      <concept>
        <code value="4010104"/>
        <display value="Pleomorphic liposarcoma"/>
      </concept>
      <concept>
        <code value="1243142"/>
        <display value="Myxoid pleomorphic liposarcoma"/>
      </concept>
      <concept>
        <code value="4264204"/>
        <display value="Aggressive fibromatosis"/>
      </concept>
      <concept>
        <code value="4295283"/>
        <display value="Dermatofibrosarcoma protuberans"/>
      </concept>
      <concept>
        <code value="4207381"/>
        <display value="Epithelioid haemangioendothelioma"/>
      </concept>
      <concept>
        <code value="3661612"/>
        <display value="Angiosarcoma"/>
      </concept>
      <concept>
        <code value="4029021"/>
        <display value="Undifferentiated sarcoma"/>
      </concept>
      <concept>
        <code value="4239519"/>
        <display value="Myoepithelioma"/>
      </concept>
      <concept>
        <code value="4029680"/>
        <display value="Myoepithelial carcinoma"/>
      </concept>
      <concept>
        <code value="4028565"/>
        <display value="Ossifying fibromyxoid tumour"/>
      </concept>
      <concept>
        <code value="4195947"/>
        <display value="Mesenchymoma"/>
      </concept>
      <concept>
        <code value="45766484"/>
        <display value="Phosphaturic mesenchymal tumor, benign"/>
      </concept>
      <concept>
        <code value="45766485"/>
        <display value="Phosphaturic mesenchymal tumour, malignant"/>
      </concept>
      <concept>
        <code value="4239956"/>
        <display value="Angiomyxoma"/>
      </concept>
      <concept>
        <code value="4029526"/>
        <display value="Angiomatoid fibrous histiocytoma"/>
      </concept>
      <concept>
        <code value="45766528"/>
        <display value="Ewing sarcoma / peripheral neuroectodermal tumor"/>
      </concept>
      <concept>
        <code value="37311513"/>
        <display value="Biphenotypic sinonasal sarcoma"/>
      </concept>
      <concept>
        <code value="4135215"/>
        <display value="Adenosarcoma"/>
      </concept>
    </include>
    <include>
      <system
              value="http://hl7.eu/fhir/ig/idea4rc/CodeSystem/cs-idea4rc-vocab-eu-i4rc"/>
      <concept>
        <code value="2000100012"/>
        <display
                 value="Non-keratinizing squamous cell carcinoma: SMARCB1 (INI-1)-deficient Sinonasal Carcinoma"/>
      </concept>
      <concept>
        <code value="2000100013"/>
        <display
                 value="Non-keratinizing squamous cell carcinoma: Transitional (cylindrical cell, Schneiderian) carcinoma"/>
      </concept>
      <concept>
        <code value="2000100014"/>
        <display
                 value="Spindle cell (sarcomatoid) squamous cell carcinoma: SMARCB1 (INI-1)"/>
      </concept>
      <concept>
        <code value="2000100015"/>
        <display
                 value="SMARCB1 (INI-1)-deficient Sinonasal undifferentiated Carcinoma"/>
      </concept>
      <concept>
        <code value="2000100016"/>
        <display value="Sinonasal SMARCA4 deficient carcinoma"/>
      </concept>
      <concept>
        <code value="2000100017"/>
        <display value="IDH2-mutated sinonasal undifferentiated neoplasm"/>
      </concept>
      <concept>
        <code value="2000100018"/>
        <display value="HPV-related Multiphenotypic Sinonasal Carcinoma"/>
      </concept>
      <concept>
        <code value="2000100019"/>
        <display value="NTRK-rearranged spindle cell neoplasm (emerging)"/>
      </concept>
    </include>
  </compose>
</ValueSet>